101953-61-1

Basic information

• Product Name: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
• Synonyms: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE;1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2(3H)-one;1-(2-Ethoxyethyl)-1,3-dihydro-2H-benzimidazol-2-one;1-(2-ethoxyethyl)benziMidazone/"BenziMidazolone;1-(2-ETHOXYETHYL)-1,3-DIHYDRO-2H-BENZO[D]IMIDAZOL-2-ONE
• CAS NO: 101953-61-1
• Molecular Formula: C11H14N2O2
• Molecular Weight: 206.24
• Mol File: 101953-61-1.mol

Chemical Properties

• Boiling Point: 393.8 °C at 760 mmHg
• Flash Point: 192 °C
• Appearance: /
• Density: 1.151
• CAS DataBase Reference: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE(101953-61-1)
• EPA Substance Registry System: 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE(101953-61-1)

Safety Data

• Hazardous Substances Data: 101953-61-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE is used as an active ingredient in medications for the treatment of hypertension and anxiety, among other medical conditions. Its incorporation into pharmaceutical formulations is due to its ability to address specific health issues effectively.
Used in Agrochemical Industry:
As an intermediate in the synthesis of agrochemicals, 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE contributes to the development of products that enhance agricultural productivity and crop protection.
Used in Organic Compounds Production:
1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE is used as a building block in the production of various organic compounds, highlighting its utility in creating a range of chemical products with diverse applications.
Used in Drug Development Research:
1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE is also used in the research and development of novel drugs, where its unique properties are harnessed to explore new therapeutic avenues and improve existing medications.
Overall, 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE is a multifaceted chemical with significant applications across different industries, underscoring its importance in modern chemical and medical advancements.

Upstream product

• 95893-89-3 N-(β-ethoxyethyl)-o-phenylenediamine 
• 57-13-6 urea 
• 88-73-3 2-Chloronitrobenzene 
• 95893-88-2 N-(β-ethoxyethyl)-o-nitroaniline 
• 4926-55-0 2-[(2-nitrophenyl)amino]ethanol 

Downstream Products

• 101954-18-1 2-(4-Benzhydryl-piperazin-1-yl)-1-(2-ethoxy-ethyl)-1H-benzoimidazole 
• 101954-16-9 1-(2-Ethoxy-ethyl)-2-(4-phenethyl-piperazin-1-yl)-1H-benzoimidazole 
• 87233-79-2 2-(4-benzyl-1-piperazinyl)-1-(2-ethoxyethyl)benzimidazole 
• 101954-30-7 2-(4-Benzyl-[1,4]diazepan-1-yl)-1-(2-ethoxy-ethyl)-1H-benzoimidazole 
• 101954-15-8 1-(2-Ethoxy-ethyl)-2-(4-phenyl-piperazin-1-yl)-1H-benzoimidazole 
• 87233-54-3 1-(2-ethoxyethyl)-2-chloro-1H-benzimidazole 

Relevant articles and documents

Synthesis and antihistaminic H1 activity of 1,2,5(6)-trisubstituted benzimidazoles

A number of benzimidazoles, having several substituents on the azole and benzene nuclei and C-2 (methylamino, ethylenediamine, morpholine, piperazine and piperidine) were prepared. Regioselective synthesis was designed for the N1-alkyl substituted benzimidazoles (14-15). X-Ray structure analysis of (14) was also revealed. Compounds were evaluated for their in vitro H1- antihistaminic activity in the isolated guinea-pig ileum method. The compound (11) exhibits best activity.