- Synthesis of benzylaminopyrimidines and their fungicidal activities against wheat brown rust and barley powdery mildew
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Members of a new class of fungicide containing benzyl-aminopyrimidine as a core structure were synthesized and their fungicidal potencies against wheat brown rust, Puccinia recondita, and barley powdery mildew, Erysiphe graminis, were assessed. Among these fungicides, N-(fluoroalkoxy or fluorophenoxybenzyl)-4-pyrimidinamines showed notable preventive activities. The potency of the new pyrimidines was increased when a difluoromethoxy or tetrafluorophenoxy group was introduced at the 4- or 3-position of the phenyl moiety and a methyl or ethyl group was introduced at the benzyl position. Structure-activity relationships are discussed.
- Yamanaka,Moritomo,Fujii,Tanaka,Fukuda,Nishimura
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p. 223 - 229
(2007/10/03)
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- 6-(polyfluoroalkoxyphenyl) pyridazinones, their compositions, synthesis and use
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6-aryl-3[2H]pyridazinones of formula I STR1 in which one of the substituents R1 and R2 denotes hydrogen or (C1-C4)-alkoxy, and the other denotes polyfluoro-(C1-C4)-alkoxy, and their pharmacologically-tolerated salts are suitable as bronchospasmolytic and cardiotonic active compounds. Processes for their preparation and appropriate medicaments are indicated.
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