Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis
The cross-coupling of aryl bromides with [11C]CH3Li for the labelling of a variety of tracers for positron emission tomography (PET) is presented. The radiolabelled products were obtained in excellent yields, at rt and after short reaction times (3-5 min) compatible with the half-life of 11C (20.4 min). The automation of the protocol on a synthesis module is investigated, representing an important step towards a fast method for the synthesis of 11C-labelled compounds for PET imaging. This journal is
Helbert, Hugo,Antunes, Ines Farinha,Luurtsema, Gert,Szymanski, Wiktor,Feringa, Ben L.,Elsinga, Philip H.
supporting information
p. 203 - 206
(2021/01/13)
Metal-Free Synthesis of 2-Arylbenzothiazoles from Aldehydes, Amines, and Thiocyanate
A highly efficient method for the synthesis of 2-arylbenzothiazoles has been developed using readily available aromatic amines, benzaldehydes, and NH4SCN as a sulfur source. A library of 2-arylbenzothiazoles with wide functional group compatibility has been synthesized in good yields through iodine-mediated oxidative annulation.
Dey, Amrita,Hajra, Alakananda
supporting information
p. 1686 - 1689
(2019/03/11)
A convenient method for synthesis of benzo[d]thiazoles in water and solvent free condition
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Yoon, Soon Byung,Chun, Eun Jeong,Noh, Young Ri,Yoon, Yong Jin,Lee, Sang-Geyong