Organocatalytic kinetic resolution via intramolecular aldol reactions: Enantioselective synthesis of both enantiomers of chiral cyclohexenones
Kinetic resolution of 6-aryl-2,6-hexanediones was achieved with chiral secondary amine catalyzed intramolecular aldolization. The current kinetic resolution protocol enables the synthesis of both enantiomers of cyclohexenones with moderate to good enantioselectivity. The Royal Society of Chemistry 2010.
Efficient iron-catalyzed sakurai-michael addition of allyltrimethylsilane to chalcones
A general catalytic conjugate addition with allyltrimethylsilane and chalcones is described. Allyltrimethylsilane undergoes the Sakurai-Michael reaction smoothly with high chemoselectivity in the presence of a catalytic amount of FeCl3/TMSCl under very mi