Novel c-2 substituted carbapenem derivatives. Part IV. Synthesis and biological activity of five membered heteroaromatic derivatives
The synthesis, antibacterial activity, and stability to human dehydropeptidase-1 (DHP-1) of a novel series of (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-heterocyclylcarbapen-2-em-3-carboxylates are described. Of the compounds investigated 1,5-disubstituted pyrazol
Branch, Clive L.,Burton, George,Clarke, Graham J.,Coulton, Steven,Douglas, James D.,Eglington, A. John,Guest, Angela W.,Hinks, Jeremy D.,Hird, Nicholas W.,Holland, Rebecca K.,Hunt, Eric,Knott, Sarah J.,Moss, Stephen F.,Naylor, Antoinette,Pearson, Michael J.,Takle, Andrew K.
p. 210 - 220
(2007/10/03)
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