102601-58-1

Basic information

• Product Name: Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN
• Synonyms: N-CBZ-GLY-GLY-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;N-CBZ-GLY-GLY-ARG-AMC HCL;N-CBZ-GLYCYL-GLYCYL-L-ARGININE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;N-ALPHA-CARBOBENZOXY-GLYCYLGLYCYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE;N-CARBOBENZOXY-L-GLYCYL-L-GLYCYL-L-ARGININE 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;N-CARBOBENZOXY-GLYCYLGLYCYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE;N-CBZ-GLY-GLY-ARG 7-AMIDO-4-METHYLCOUMAR IN HYDROCH;Z-Gly-Gly-Arg-Amc hydrochloride
• CAS NO: 102601-58-1
• Molecular Formula: C28H33N7O7
• Molecular Weight: 579.6
• Product Categories: Coagulation Proteins and ReagentsEnzyme Substrates;Plasma&Blood Proteins;Protease Substrates;Proteins and Derivatives;Substrates by Enzyme;Urokinase;UrokinaseEnzyme Substrates;proteins
• Mol File: 102601-58-1.mol

Chemical Properties

• Boiling Point: 1000.9°C at 760 mmHg
• Flash Point: 559.1°C
• Appearance: /
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN(102601-58-1)
• EPA Substance Registry System: Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN(102601-58-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 102601-58-1(Hazardous Substances Data)

Usage

Uses

Used in Research Applications:
Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN is used as a research tool for studying the activity of urokinase (uPA) enzyme. It allows researchers to monitor the enzymatic activity in various experimental setups, such as in vitro assays and cell culture studies.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN is used as a starting point for the development of potential drugs targeting urokinase (uPA) enzyme. By understanding the interactions between this substrate and the enzyme, researchers can design inhibitors or modulators that can be used in the treatment of diseases associated with uPA activity.
Used in Diagnostic Applications:
Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN can be employed in diagnostic assays to detect and measure the activity of urokinase (uPA) enzyme in biological samples. This can be useful in the diagnosis and monitoring of diseases where uPA activity is implicated, such as cancer and thrombotic disorders.
Used in Drug Screening:
Z-GLY-GLY-ARG-7-AMINO-4-METHYLCOUMARIN is used in high-throughput screening assays to identify potential inhibitors or activators of urokinase (uPA) enzyme. This helps in the discovery of new compounds that can modulate uPA activity and be further developed as therapeutic agents.

InChI:InChI=1/C28H33N7O7.ClH/c1-17-12-25(38)42-22-13-19(9-10-20(17)22)34-26(39)21(8-5-11-31-27(29)30)35-24(37)15-32-23(36)14-33-28(40)41-16-18-6-3-2-4-7-18;/h2-4,6-7,9-10,12-13,21H,5,8,11,14-16H2,1H3,(H,32,36)(H,33,40)(H,34,39)(H,35,37)(H4,29,30,31);1H