Conjugates of podophyllotoxin and norcantharidin as dual inhibitors of topoisomeraseⅡ and protein phosphatase 2A
A series of novel conjugates of podophyllotoxin and norcantharidin was designed using association strategy, and synthesized by coupling 4′-demethylepipodophyllotoxin with N-amino acid norcantharimides, and their cytotoxicitiy was evaluated against four hu
Amide compounds for regulating WNT signal channel and application of compounds
The invention belongs to the technical field of medicine, and particularly relates to amide compounds for regulating a WNT signal channel and an application of the compounds. The compounds have a structure represented by a general formula I shown in the description.
-
Paragraph 0293; 0295
(2019/07/11)
COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS
The present application discloses the Tv-stp-1 serine/threonine phosphatase gene from Trichostrongylus vitrinus, and compounds that are useful as invertebrate control agents.
-
Page/Page column 74
(2008/12/05)
Norcantharimides, synthesis and anticancer activity: Synthesis of new norcantharidin analogues and their anticancer evaluation
A range of amines was reacted with norcantharidin (2) to provide the corresponding norcantharimides (9-43). Treatment of norcantharidin with allylamine afforded the corresponding allyl-norcantharimide (20) which was amenable to epoxidation (mCPBA, 22) and
Hill, Timothy A.,Stewart, Scott G.,Ackland, Stephen P.,Gilbert, Jayne,Sauer, Benjamin,Sakoff, Jennette A.,McCluskey, Adam
p. 6126 - 6134
(2008/03/27)
Synthesis and Anticonvulsant Activity of 7-Oxabicycloheptane Derivatives: Part 1 - N-Alkyl, N-Aryl and N-Heteroaryl Derivatives of 3,6-Epoxyhexahydrophthalimide
A series (sixty one) of N-substituted 3,6-epoxyhexahydrophthalimides have been prepared by the condensation of the appropriately substituted alkyl, aryl and heteroarylamines with exo-cis-3,6-epoxyhexahydrophthalic anhydride (2).Some of the compounds exhib
Joshi, Balawant S.,David, Joy,Gawad, Dilip H.
p. 131 - 135
(2007/10/02)
More Articles about upstream products of 1026678-11-4