102791-74-2

Basic information

• Product Name: 6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate (1:1)
• CAS NO: 102791-74-2
• Molecular Formula: C₁₆H₁₉N₃O₄S
• Molecular Weight: 349.4048
• Mol File: 102791-74-2.mol

Chemical Properties

• Boiling Point: 666.5°C at 760 mmHg
• Flash Point: 356.9°C
• Vapor Pressure: 1.14E-18mmHg at 25°C
• CAS DataBase Reference: 6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate (1:1)(102791-74-2)
• EPA Substance Registry System: 6-(2,4-dimethyl-1H-imidazol-1-yl)-8-methylquinolin-2(1H)-one methanesulfonate (1:1)(102791-74-2)

Safety Data

• Hazardous Substances Data: 102791-74-2(Hazardous Substances Data)

Relevant articles and documents

6-heteroaryl quinolone inotropic agents

A series of novel heterocyclic-substituted 2-(1H)-quinolone compounds have been prepared, including the 3,4-dihydro derivatives thereof, wherein the heterocyclic ring moiety is a pyrrolyl, imidazolyl, pyrazolyl, triazolyl or tetrazolyl group attached by a nitrogen atom of said group to the 5-, 6-, 7- or 8-positions of the quinolone ring. These particular compounds are useful in therapy as highly potent inotropic agents and therefore, are of value in the treatment of various cardiac conditions. Preferred member compounds include 6-(2,4-dimethylimidazol-1-yl)-8-methyl-2-(1H)-quinolone, 6-(2,4-dimethyl-5-nitroimadazol-1-yl)-8-methyl-2-(1H)-quinolone, 8-methyl-6-(tetrazol-1-yl)-2-(1H)-quinolone, 8-methyl-6-(1,2,4-triazol-4-yl)-2-(1H)-quinolone, and 6-(4-cyano-2-methylimidazol-1-yl)-8-methyl-2-(1H)-quinolone, respectively. Methods for preparing these compounds from known starting materials are provided.