102804-44-4 Usage
Uses
Used in Organic Synthesis:
(2E)-N-(2-bromophenyl)but-2-enamide is used as a starting material or intermediate for the synthesis of various organic compounds. Its unique structure and functional groups make it a valuable building block for the development of new molecules with specific properties.
Used in Medicinal Chemistry:
(2E)-N-(2-bromophenyl)but-2-enamide is used as a starting material or intermediate for the production of pharmaceuticals and biologically active molecules. Its bromine-substituted phenyl group and amide functionality can be utilized to design and synthesize new drugs with improved therapeutic properties.
Used in Drug Development:
(2E)-N-(2-bromophenyl)but-2-enamide is used as a building block for the development of new drugs. Its unique structure and functional groups can be modified to create novel drug candidates with potential therapeutic applications.
Used in Agrochemical Development:
(2E)-N-(2-bromophenyl)but-2-enamide is used as a building block for the development of new agrochemicals. Its potential as a versatile chemical compound can be harnessed to create new pesticides, herbicides, or other agricultural chemicals with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 102804-44-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,8,0 and 4 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 102804-44:
(8*1)+(7*0)+(6*2)+(5*8)+(4*0)+(3*4)+(2*4)+(1*4)=84
84 % 10 = 4
So 102804-44-4 is a valid CAS Registry Number.
102804-44-4Relevant articles and documents
Solid-phase synthesis of indol-2-ones by microwave-assisted radical cyclization
Akamatsu, Hisashi,Fukase, Koichi,Kusumoto, Shoichi
, p. 1049 - 1053 (2007/10/03)
Solid-phase synthesis of indol-2-ones (2-oxindoles) by means of aryl radical cyclization of resin-bound N-(2-bromophenyl)acrylamides using Bu 3SnH is described. Among various solvents tested, DMF was found to be the best choice for the radical cyclization inducing a reagent concentration effect of the polymer support. The reaction proceeded smoothly under microwave irradiation to give the desired indol-2-ones within a very short reaction time in comparison to conventional thermal heating. In this reaction, various indol-2-ones were synthesized by using commercially available 2-bromoanilines and acryloyl chloride derivatives.
Aryl Radical Cyclisations involving an Amide Group in the Linking Chain
Jones, Keith,Storey, John M. D.
, p. 1766 - 1767 (2007/10/02)
Cyclisation of 7, 8 and 9 via their derived aryl radicals gives products arising from addition of the aryl radical to the acryloyl double bond exclusively.
An Efficient Synthesis of Spiro via Radical Cyclisation
Jones, Keith,Thompson, Mervyn,Wright, Colin
, p. 115 - 116 (2007/10/02)
Treatment of the o-bromo-N-acryloylanilides (4) with tri-n-butylstannane leads to the formation of 3-substituted- and 3,3-disubstituted-2-oxindoles (5) in high yield.
