102846-12-8 Usage
Uses
Used in Pharmaceutical Industry:
3-(bromomethyl)-1H-pyrazole is used as a reactant for the preparation of amino dicyanopyridine derivatives, which act as non-nucleoside-like agonists of the human adenosine A2B receptor. This application is significant in the development of drugs targeting adenosine receptors, which play a crucial role in various physiological processes.
Used in Antiviral Drug Development:
In the field of antiviral research, 3-(bromomethyl)-1H-pyrazole serves as a reactant in the synthesis of 2-?(((5-?akly?/aryl-?1H-?pyrazol-?3-?yl)?methyl)?thio)?-?5-?alkyl-?6-?(cyclohexylmethyl)?-?pyrimidin-?4(3H)?-?one derivatives. These compounds have the potential to act as HIV-1 inhibitors, offering a promising avenue for the development of new treatments against the human immunodeficiency virus.
Used in the Synthesis of Macrocyclic Ligands:
3-(bromomethyl)-1H-pyrazole is also utilized as a reactant in the preparation of macrobicyclic ligands containing pyrazole subunits, such as the N, N’-bipyrazolyl cryptand. These macrocyclic ligands have potential applications in supramolecular chemistry, coordination chemistry, and as catalysts or receptors for various substrates.
Check Digit Verification of cas no
The CAS Registry Mumber 102846-12-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,8,4 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 102846-12:
(8*1)+(7*0)+(6*2)+(5*8)+(4*4)+(3*6)+(2*1)+(1*2)=98
98 % 10 = 8
So 102846-12-8 is a valid CAS Registry Number.
102846-12-8Relevant articles and documents
Synthesis of Macrobicyclic Ligands containing Pyrazole Subunits: the N,N'-Bipyrazolyl Cryptand
Juanes, Olga,Mendoza, Javier de,Rodriguez-Ubis, Juan-Carlos
, p. 1765 - 1766 (2007/10/02)
The pyrazolyl cryptands (1) and (2) have been obtained in one-step, non high-dilution macrobicyclization reaction, from a 1,1'-bipyrazole derivative; similarly, tripodal ligands (7)-(9) with pyrazole structures are described.
