1029720-67-9

Basic information

• Product Name: 5-broMo-3-chloroisoquinoline
• Synonyms: 5-broMo-3-chloroisoquinoline
• CAS NO: 1029720-67-9
• Molecular Formula: C₉H₅BrClN
• Molecular Weight: 242.4997
• EINECS: -0
• Mol File: 1029720-67-9.mol

Chemical Properties

• Boiling Point: 349.5±22.0 °C(Predicted)
• Appearance: /
• Density: 1.673±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 0.86±0.43(Predicted)
• CAS DataBase Reference: 5-broMo-3-chloroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-3-chloroisoquinoline(1029720-67-9)
• EPA Substance Registry System: 5-broMo-3-chloroisoquinoline(1029720-67-9)

Safety Data

• Hazardous Substances Data: 1029720-67-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
5-Bromo-3-chloroisoquinoline serves as a building block in the synthesis of pharmaceuticals, contributing to the development of new drugs with potential therapeutic applications. Its unique structure and reactivity facilitate the creation of diverse organic compounds, making it a valuable component in medicinal chemistry.
Used in Agrochemicals:
In the agrochemical industry, 5-bromo-3-chloroisoquinoline is utilized as a precursor for the synthesis of various agrochemicals, including pesticides and herbicides. Its chemical properties allow for the development of effective compounds that protect crops and enhance agricultural productivity.
Used in Chemical Research:
5-Bromo-3-chloroisoquinoline is employed as a valuable tool in chemical research, particularly for studying chemical reactions and mechanisms. Its distinct structure provides insights into the behavior of isoquinoline derivatives and their interactions with other molecules, furthering our understanding of organic chemistry.

Upstream product

• 58142-49-7 3-chloro-5-amino-isoquinoline 
• 7742-73-6 1,3-dichloroisoquinoline 
• 1215767-89-7 5-bromo-1,3-dichloroisoquinoline 

Downstream Products

• 1254715-58-6 C₁₄H₁₄ClNO₂ 
• 1578243-56-7 tert-butyl 4-(4-(3-((2-methoxy-4-(3-methoxyazetidine-1-carbonyl)phenyl)amino)isoquinolin-5-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate 
• 1578243-72-7 (3-methoxy-4-((5-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-73-8 (3-methoxy-4-((5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-75-0 (3-chloro-4-((5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-81-8 5-(furan-2-yl)-N-(4-methoxyphenyl)isoquinolin-3-amine 
• 1578243-84-1 N-(2-methoxy-4-((1-methylpiperidin-4-yl)oxy)phenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 
• 1578243-86-3 N-(2,4-dimethoxyphenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 
• 1578243-54-5 (4-((5-(1-(2-(dimethylamino)ethyl)-1H-pyrazol-4-yl)isoquinolin-3-yl)amino)-3-methoxyphenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-74-9 (3-methoxy-4-((5-(pyridin-3-yl)isoquinolin-3-yl)amino)phenyl)(3-methoxyazetidin-1-yl)methanone 
• 1578243-82-9 N-(4-methoxyphenyl)-5-(1-methyl-1H-pyrazol-4-yl)isoquinolin-3-amine 

Relevant articles and documents

METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS

The subject matter described herein is directed to ferroportin inhibitor compounds of Formula (I) and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).