The invention describes a one pot process for synthesizing a compound of structure (I), or a tautomer thereof. A compound of structure (II), or a tautomer thereof, and an aldehyde of structure RdCHO are condensed to form a condensation product.
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Page/Page column 37
(2010/01/12)
Synthesis and dehydrogenation of spinaceamine and spinacine 4-hetaryl derivatives
The reaction of histamine and histidine with various hetarylaldehydes under the conditions of the base-catalyzed Pictet-Spengler process affords 4-hetaryl-substituted derivatives of spinaceamine and spinacine. The dehydrogenation of the 4-hetaryl-substitu
Smolyar,Abramyants,Zavyazkina,Matveeva,Borodkin, Ya. S.,Voloskii
experimental part
p. 1219 - 1223
(2009/12/09)
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