1031857-98-3 Usage
Uses
Used in Pharmaceutical Development:
4-Borono-3,5-difluorobenzoic acid is utilized as a precursor in the synthesis of various pharmaceuticals, particularly for the development of new drugs. Its unique structure allows for the design of molecules with potential therapeutic applications, including the treatment of cancer and other diseases.
Used in Biochemical Research:
In the field of biochemical research, 4-Borono-3,5-difluorobenzoic acid is employed as a binding agent to certain proteins and enzymes. Its ability to interact with these biological targets makes it a valuable tool for studying enzyme mechanisms, protein functions, and the development of targeted therapies.
Used in Organic Synthesis:
4-Borono-3,5-difluorobenzoic acid is used as a versatile building block in organic synthesis. Its reactivity and structural features facilitate the creation of a wide range of organic compounds, contributing to the advancement of chemical research and the discovery of novel chemical entities.
Used in Medicinal Chemistry:
In medicinal chemistry, 4-Borono-3,5-difluorobenzoic acid is applied as a key component in the design and synthesis of biologically active molecules. Its incorporation into drug candidates can enhance their pharmacological properties, such as potency, selectivity, and bioavailability, thereby improving their therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 1031857-98-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,1,8,5 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1031857-98:
(9*1)+(8*0)+(7*3)+(6*1)+(5*8)+(4*5)+(3*7)+(2*9)+(1*8)=143
143 % 10 = 3
So 1031857-98-3 is a valid CAS Registry Number.
1031857-98-3Relevant articles and documents
Dual isotope labeling: Conjugation of 32P-oligonucleotides with 18F-aryltrifluoroborate via copper(I) catalyzed cycloaddition
Li, Ying,Schaffer, Paul,Perrin, David M.
, p. 6313 - 6316 (2013)
A one-pot-two-step labeling of an oligonucleotide with an 18F-ArBF3-(aryltrifluoroborate) radioprosthetic is reported herein. In order to characterize labeling in terms of radiochemistry, phosphorus-32 was also introduced
Synthesis and characterization of 2,6-difluoro-4-carboxyphenylboronic acid and a biotin derivative thereof as captors of anionic aqueous [18F]-fluoride for the preparation of [18F/19F]-labeled aryltrifluoroborates with high kinetic stability
Harwig, Curtis W.,Ting, Richard,Adam, Michael J.,Ruth, Thomas J.,Perrin, David M.
, p. 3152 - 3156 (2008/09/20)
Arylboronic esters are readily converted to aryltrifluoroborates in the presence of aqueous fluoride. As such these represent attractive synthetic precursors that afford one-step labeling with [18F]-fluoride for the generation of PET reagents. Herein we present the synthesis of a heretofore undisclosed arylboronic ester that is converted to its corresponding trifluoroborate. Essential for contemplating its use in PET imaging is the demonstration of kinetic resistance to solvolytic defluoridation.
