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6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester is a boronic acid pinacol ester derivative of 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid, a chemical compound utilized in organic synthesis and medicinal chemistry. It serves as a building block in the creation of pharmaceuticals and agrochemicals, with the pinacol ester group enhancing its stability and solubility, facilitating easier handling and storage.

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  • 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester

    Cas No: 1032758-87-4

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  • 1032758-87-4 Structure
  • Basic information

    1. Product Name: 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester
    2. Synonyms: 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester
    3. CAS NO:1032758-87-4
    4. Molecular Formula: C17H27BN2O4
    5. Molecular Weight: 352.23356
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1032758-87-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 435.7ºC at 760 mmHg
    3. Flash Point: 217.3ºC
    4. Appearance: /
    5. Density: 1.09g/cm3
    6. Vapor Pressure: 8.58E-08mmHg at 25°C
    7. Refractive Index: 1.506
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester(1032758-87-4)
    12. EPA Substance Registry System: 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester(1032758-87-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1032758-87-4(Hazardous Substances Data)

1032758-87-4 Usage

Uses

Used in Pharmaceutical Industry:
6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester is used as a key intermediate for the synthesis of biologically active compounds, contributing to the development of new drug candidates. Its role in medicinal chemistry is pivotal, as it aids in the construction of molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester is employed as a building block in the synthesis of agrochemicals, playing a crucial role in the development of new compounds designed to protect crops and enhance agricultural productivity.
The versatility of 6-(tert-Butyloxycarbonyl-methylamino)pyridine-3-boronic acid pinacol ester in both pharmaceutical and agrochemical industries underscores its importance as a synthetic intermediate, highlighting its potential to contribute to advancements in these fields.

Check Digit Verification of cas no

The CAS Registry Mumber 1032758-87-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,2,7,5 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1032758-87:
(9*1)+(8*0)+(7*3)+(6*2)+(5*7)+(4*5)+(3*8)+(2*8)+(1*7)=144
144 % 10 = 4
So 1032758-87-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H27BN2O4/c1-15(2,3)22-14(21)20(8)13-10-9-12(11-19-13)18-23-16(4,5)17(6,7)24-18/h9-11H,1-8H3

1032758-87-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H27430)  6-(N-Boc-methylamino)pyridine-3-boronic acid pinacol ester, 95%   

  • 1032758-87-4

  • 250mg

  • 1476.0CNY

  • Detail
  • Alfa Aesar

  • (H27430)  6-(N-Boc-methylamino)pyridine-3-boronic acid pinacol ester, 95%   

  • 1032758-87-4

  • 1g

  • 3669.0CNY

  • Detail

1032758-87-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-Butyl methyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)carbamate

1.2 Other means of identification

Product number -
Other names tert-butyl N-methyl-N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]carbamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1032758-87-4 SDS

1032758-87-4Downstream Products

1032758-87-4Relevant articles and documents

SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE

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Page/Page column 261, (2017/08/01)

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell proliferative disorders, such as cancer, wherein A, R2, R3, R10, E1, E2, E3, Y, and Z are as defined herein.

THIAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

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Page/Page column 84, (2009/05/29)

Compounds of Formulas (Ia and Ib), and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed

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