1034152-93-6

Basic information

• Product Name: 2-(3-(6-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-(trifluoromethyl)-6,11-dihydro-5H-benzo[b]pyrido[2,3-e][1,4]diazepin-7-yl)-1,2,4-oxadiazol-5-yl)propan-2-ol
• Synonyms: MK-7725;2-(3-(6-((4-(trifluoroMethoxy)phenyl)sulfonyl)-2-(trifluoroMethyl)-6,11-dihydro-5H-benzo[b]pyrido[2,3-e][1,4]diazepin-7-yl)-1,2,4-oxadiazol-5-yl)propan-2-ol
• CAS NO: 1034152-93-6
• Molecular Formula: C25H19F6N5O5S
• Molecular Weight: 615.513
• Mol File: 1034152-93-6.mol

Chemical Properties

• CAS DataBase Reference: 2-(3-(6-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-(trifluoromethyl)-6,11-dihydro-5H-benzo[b]pyrido[2,3-e][1,4]diazepin-7-yl)-1,2,4-oxadiazol-5-yl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-(6-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-(trifluoromethyl)-6,11-dihydro-5H-benzo[b]pyrido[2,3-e][1,4]diazepin-7-yl)-1,2,4-oxadiazol-5-yl)propan-2-ol(1034152-93-6)
• EPA Substance Registry System: 2-(3-(6-((4-(trifluoromethoxy)phenyl)sulfonyl)-2-(trifluoromethyl)-6,11-dihydro-5H-benzo[b]pyrido[2,3-e][1,4]diazepin-7-yl)-1,2,4-oxadiazol-5-yl)propan-2-ol(1034152-93-6)

Safety Data

• Hazardous Substances Data: 1034152-93-6(Hazardous Substances Data)

Usage

Molecular structure

The compound has a complex structure consisting of a central core with a benzopyrido-diazepin structure, attached functional groups, and a propan-2-ol moiety.

Functional groups

The compound contains several functional groups, including a trifluoromethyl group, a sulfonyl group, an oxadiazol group, and a trifluoromethoxyphenyl group.

Trifluoromethyl group

This group (CF3) is attached to the benzopyrido-diazepin core and is known for its high electronegativity and stability.

Sulfonyl group

The sulfonyl group (SO2) is connected to the phenyl ring and is known for its ability to act as a good leaving group in reactions and can influence the compound's reactivity.

Oxadiazol group

The 1,2,4-oxadiazol group is present in the molecule and is known for its potential pharmacological properties, such as acting as a receptor antagonist.

Trifluoromethoxyphenyl group

This group (OC(CF3)3) is attached to the phenyl ring and can influence the compound's solubility, stability, and pharmacokinetic properties.

Propan-2-ol moiety

The compound also features a propan-2-ol group (CH3CH(OH)CH3), which can participate in hydrogen bonding and solvation, potentially affecting the compound's solubility and pharmacokinetic properties.

Pharmacological properties

The compound is likely to have specific pharmacological properties due to its complex structure and the presence of various functional groups, making it a potential candidate for pharmaceutical research and drug development.

Application in drug development

The compound's unique structure and functional groups may contribute to its potential use in the development of new drugs for various therapeutic applications.

Upstream product

• 1034046-86-0 7-cyano-6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine 
• 1034046-87-1 C₂₁H₁₅F₆N₅O₄S 
• 1034044-50-2 2-{3-[6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl}propan-2-ol 

Downstream Products

• 1034044-50-2 2-{3-[6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl}propan-2-ol 
• 1034044-50-2 2-{3-[6-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-(trifluoromethyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl}propan-2-ol 

Relevant articles and documents

Discovery of MK-7725, a potent, selective bombesin receptor subtype-3 agonist for the treatment of obesity

Extensive structure-activity relationship studies of a series derived from atropisomer 1, a previously described chiral benzodiazepine sulfonamide series, led to a potent, brain penetrant and selective compound with excellent preclinical pharmacokinetic a