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(2-Methylpyrimidin-5-yl)boronic acid is a chemical compound that belongs to the class of organic compounds known as pyrimidines and pyrimidine derivatives. It features a pyrimidine ring, a six-member aromatic heterocycle with two nitrogen atoms at positions 1 and 3, similar to benzene and pyridine. The boronic acid functional group in this compound allows for the formation of boronate by condensation with a diol. (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID is primarily used in pharmaceutical research and development due to its properties in chemical reactions. However, it requires careful handling due to potential harmful or unsafe effects.

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  • 1034924-06-5 Structure
  • Basic information

    1. Product Name: (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID
    2. Synonyms: (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID;2-Methylpyrimidine-5-boronic acid;(2-Methyl-5-pyriMidinyl)-boronic acid;B-(2-Methyl-5-pyrimidinyl)boronic acid;5-Borono-2-methylpyrimidine, 5-Borono-2-methyl-1,3-diazine
    3. CAS NO:1034924-06-5
    4. Molecular Formula: C5H7BN2O2
    5. Molecular Weight: 137.93228
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1034924-06-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 308.3±34.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.26
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerated.
    8. Solubility: N/A
    9. PKA: 5.48±0.11(Predicted)
    10. CAS DataBase Reference: (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID(1034924-06-5)
    12. EPA Substance Registry System: (2-METHYLPYRIMIDIN-5-YL)BORONIC ACID(1034924-06-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1034924-06-5(Hazardous Substances Data)

1034924-06-5 Usage

Uses

Used in Pharmaceutical Research and Development:
(2-Methylpyrimidin-5-yl)boronic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its boronic acid functional group enables the formation of boronate, which is crucial in many chemical reactions, making it a valuable component in the development of new drugs and therapeutic agents.
Used in Chemical Reactions:
In the field of organic chemistry, (2-Methylpyrimidin-5-yl)boronic acid is used as a reagent in various chemical reactions. Its ability to form boronate with diols allows for the creation of new chemical bonds and the synthesis of complex molecules, which can be further utilized in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Material Science:
(2-Methylpyrimidin-5-yl)boronic acid can also be used in material science applications, where its boronic acid functional group can be employed to create new materials with unique properties. These materials could potentially be used in the development of advanced materials for electronics, coatings, or other industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1034924-06-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,4,9,2 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1034924-06:
(9*1)+(8*0)+(7*3)+(6*4)+(5*9)+(4*2)+(3*4)+(2*0)+(1*6)=125
125 % 10 = 5
So 1034924-06-5 is a valid CAS Registry Number.

1034924-06-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-Methylpyrimidin-5-yl)boronic acid

1.2 Other means of identification

Product number -
Other names 2-methylpyrimidin-5-yl boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1034924-06-5 SDS

1034924-06-5Upstream product

1034924-06-5Downstream Products

1034924-06-5Relevant articles and documents

PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA

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Page/Page column 57-58, (2017/11/01)

The instant invention provides compounds of formula (I) which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.

PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA

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Page/Page column 66; 67, (2014/06/11)

The instant invention provides compounds of formula I which are PI3K-delta inhibitors, and as such are useful for the treatment of PI3K-delta-mediated diseases such as inflamation, asthma, COPD and cancer.

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