1035261-83-6

Basic information

• Product Name: 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile
• Synonyms: 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile;4-(3-(TRIFLUOROMETHYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBONITRILE
• CAS NO: 1035261-83-6
• Molecular Formula: C₁₃H₁₂F₃NO
• Molecular Weight: 255.2356896
• Mol File: 1035261-83-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile(1035261-83-6)
• EPA Substance Registry System: 4-[3-(Trifluoromethyl)phenyl]oxane-4-carbonitrile(1035261-83-6)

Safety Data

• Hazardous Substances Data: 1035261-83-6(Hazardous Substances Data)

Usage

Molecular Structure

Contains a four-membered oxane ring and a carbonitrile group

Functional Groups

Trifluoromethyl group attached to a phenyl ring

Applications

Used in various chemical reactions
Employed as a building block for synthesizing more complex molecules
Potential applications in pharmaceutical and agrochemical industries

Potential Uses

Intermediate in the production of pharmaceutical drugs
Intermediate in the production of crop protection products

Unique Characteristics

Valuable tool for the synthesis of diverse organic compounds and materials

Upstream product

• 111-44-4 3-oxa-1,5-dichloropentane 
• 2338-76-3 3-trifluoromethylphenylacetonitrile 

Downstream Products

• 1035261-84-7 4-(3-(trifluoromethyl)phenyl)-tetrahydro-2H-pyran-4-carboxylic acid 
• 1152568-50-7 1-{4-[3-(trifluoromethyl)phenyl]tetrahydro-2H-pyran-4-yl}methanamine 
• 1294003-42-1 6-chloro-N-({4-[3-(trifluoromethyl)phenyl]tetrahydro-2H-pyran-4-yl}methyl)nicotinamide 
• 1294002-17-7 6-(4-methyl-1H-imidazol-1-yl)-N-({4-[3-(trifluoromethyl)phenyl]tetrahydro-2H-pyran-4-yl}methyl)nicotinamide 
• 902836-56-0 4-(3-(trifluoromethyl)phenyl)-tetrahydro-2H-pyran-4-carbaldehyde 
• 1356465-39-8 ethyl 3-(4-(3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-yl)propanoate 
• 1356465-41-2 tert-butyl 1-(4-(5-(2-(4-(3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-yl)ethyl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylate 
• 1356465-34-3 1-(4-(5-(2-(4-(3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-yl)ethyl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylic acid 
• 1356465-38-7 3-(4-(3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-yl)propanoic acid 
• 1356465-37-6 ethyl 3-(4-(3-(trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-yl)acrylate 
• 1040860-85-2 4-(3-(trifluoromethyl)phenyl)-tetrahydro-2H-pyran-4-carboxylic acid chloride 
• 1035261-85-8 diethyl 2-(4-(3-(trifluoromethyl)phenyl)-tetrahydro-2H-pyran-4-carbonyl)malonate 

Relevant articles and documents

SUBSTITUTED 3-PHENYL-1,2,4-OXADIAZOLE COMPOUNDS

Disclosed are compounds of Formula (I): (I) or stereoisomers, salts, or prodrugs thereof, wherein: (i) R1 and R2 are independently C1-C4 alkyl, or (ii) R1 and R2 together with the carbon atom to which they are a

SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS

Disclosed are compounds of Formula (I): [PLEASE INSERT CHEMICAL STRUCTURE HERE] or stereoisomers, N-oxides, salts, or prodrugs thereof; wherein: Ring A is phenyl or 5- to 6-membered heteroaryl; (i) R1 and R2 are independently C1-C4 alkyl; or (ii) R1 and R

NOVEL HETEROARYL IMIDAZOLES AND HETEROARYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I; (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

NOVEL PHENYL IMIDAZOLES AND PHENYL TRIAZOLES AS GAMMA-SECRETASE MODULATORS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.