A general route for the synthesis of β,β-difluorocarboxylic acids
A new method for the preparation of β,β-difluoro- (and other gem-difluoro) acids has been developed. It is based on the fact that 3-oxocarboxylic esters are easy to make and convert to the corresponding dithiane derivatives. These dithianes reacted with B
Cohen, Or,Rozen, Shlomo
p. 5362 - 5364
(2008/12/20)
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