COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES
The present invention provides novel phenylcycloalkylmethylamme derivatives, and methods of preparing phenylcycloalkylmethylamme derivatives. The present invention also provides methods of using phenylcycloalkylmethylamme derivatives and compositions of phenylcycloalkylmethylamme derivatives. The pharmaceutical compositions of the compounds of the present invention can be used for treating and/or preventing obesity and obesity related co- morbid indications and depression and depression related co-morbid indications.
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Page/Page column 56
(2013/07/19)
Novel water soluble 2,6-dimethoxyphenyl ester derivatives with intravenous anaesthetic activity
A number of water soluble bis-amino-2,6-dimethoxyphenyl ester derivatives were found to exhibit improved anaesthetic activity in mice relative to propofol 1. Of the analogues disclosed, 44 was further profiled in rodents and found to be a superior agent to propofol for the induction and maintenance of anaesthesia.
Bennett, D. Jonathan,Anderson, Alison,Buchanan, Kirsteen,Byford, Alan,Cooke, Andrew,Gemmell, David K.,Hamilton, Niall M.,Maidment, Maurice S.,McPhail, Petula,Stevenson, Donald F. M.,Sundaram, Hardy,Vijn, Peter
p. 1971 - 1975
(2007/10/03)
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