103877-75-4

Basic information

• Product Name: 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID
• Synonyms: 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID
• CAS NO: 103877-75-4
• Molecular Formula: C₈H₈FNO₂
• Molecular Weight: 169.1530232
• Product Categories: Phenylacetic acid
• Mol File: 103877-75-4.mol

Chemical Properties

• Boiling Point: 365 °C at 760 mmHg
• Flash Point: 174.5 °C
• Appearance: /
• Density: 1.356 g/cm³
• Vapor Pressure: 5.74E-06mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: 2-8°C
• PKA: 4.19±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID(103877-75-4)
• EPA Substance Registry System: 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID(103877-75-4)

Safety Data

• Hazardous Substances Data: 103877-75-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of biologically active molecules. Its unique molecular structure allows for the creation of compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID serves as an intermediate in the production of agrochemicals, leveraging its chemical properties to enhance the effectiveness of products designed for agricultural use.
Used in Organic Synthesis:
3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID is utilized in organic synthesis as a key component due to its reactive nature, facilitating the formation of a wide range of organic compounds for various applications.
Used in Medicinal Chemistry:
Within medicinal chemistry, 3-AMINO-5-FLUORO-4-METHYLBENZOIC ACID is employed for its potential to be incorporated into the structures of new pharmaceutical agents, contributing to the discovery and development of innovative medications.

InChI:InChI=1/C8H8FNO2/c1-4-6(9)2-5(8(11)12)3-7(4)10/h2-3H,10H2,1H3,(H,11,12)

Upstream product

• 400-88-4 3-nitro-4-methyl-5-fluorobenzoic acid 

Relevant articles and documents

Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity

A mutasynthetic strategy has been used to generate fluorinated TM-025 and TM-026, two biosynthetically engineered pactamycin analogues produced by Streptomyces pactum ATCC 27456. The fluorinated compounds maintain excellent activity and selectivity toward chloroquine-sensitive and multidrug-resistant strains of malarial parasites as the parent compounds. The results also provide insights into the biosynthesis of 3-aminobenzoic acid in S. pactum.

Antibacterially active alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids of the formula STR1 in which X1, X2 and X3 each independently is hydrogen, a nitro group, a halogen atom or an alkyl radical with 1 to 3 carbon atoms, with the proviso that at least one of them is an alkyl radical, or pharmaceutically acceptable salts or hydrates thereof, are antibacterially active and promote animal growth.