103930-42-3Relevant articles and documents
Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose
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, (2008/06/13)
2,6-Dideoxy-2-fluoro-L-talopyranose and 1-substituted derivatives thereof, including methyl 2,6-dideoxy-2-fluoro-L-talopyranoside and 3,4-di-O-protected-2,6-dideoxy-2-fluoro-L-talopyranosyl halides, are now provided and these new compounds are useful as i
Novel anthracycline derivatives, a process for preparing same and their use as medicaments
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, (2008/06/13)
The present invention relates to anthracycline derivatives of the general formula I where R represents the group -(CH2)mH in which m denotes 0 or an integer of 1 to 6, or the group -(CH2)nCOOH in which n de-note
SYNTHESIS OF ANTITUMOR-ACTIVE 7-O-(2,6-DIDEOXY-2-FLUORO-α-L-TALOPYRANOSYL)-DAUNOMYCINONE AND -ADRIAMYCINONE
Ok, Kwang-Dae,Takagi, Yasushi,Tsuchiya, Tsutomu,Umezawa, Sumio,Umezawa, Hamao
, p. 69 - 82 (2007/10/02)
The title compounds (17 and 23) were prepared by coupling 3,4-di-O-acetyl-2,6-dideoxy-2-fluoro-α-L-talopyranosyl bromide (15) with daunomycinone.The key step in the preparation of 15 was the epoxide-ring opening of methyl 2,3-anhydro-4-O-benzyl-6-deoxy-α-
New anthracycline derivatives, uses thereof as antitumor agent and production thereof
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, (2008/06/13)
As new anthracycline derivatives are now provided 7-O-(2,6-dideoxy-2-fluoro-α-L-talopyranosyl)daunomycinone and 7-O-(2,6-dideoxy-2-fluoro-α-L-talopyranosyl)adria-mycinone which are useful as antitumor agent and also as antibacterial agent. Briefly, these