104086-21-7Relevant articles and documents
Relationship between the ligand structure and the luminescent properties of water-soluble lanthanide complexes containing bis(bipyridine) anionic arms
Charbonniere, Loic J.,Weibel, Nicolas,Retailleau, Pascal,Ziessel, Raymond
, p. 346 - 358 (2007)
A series of six new ligands (L1-L6) suitable for the formation of luminescent lanthanide complexes in water is described. Ligands L1-L4 are constructed from two 6′-carboxy-6- methylene-2,2′-bipyridine chromophoric arms bonded to the amino function of a 2-aminomethylene-6-carboxy-pyridine (L1), an N,N-diacetate-ethylene diamine (L2), a serine (L3), or an aminomalonic acid (L4). For ligands L5 and L6, the linking amino function is provided by a glutamic acid, and the anionic functions at the 6′-position of the bipyridyl arms are made of the sodium salts of monoethylphosphonic ester (L5) and phosphonic acid (L6). The synthesis and characterisation of the ligands are described, together with the study of the formation of lanthanide complexes with europium and terbium. In the case of L3, the europium complex obtained in acidic conditions was crystallised and the X-ray crystal structure is depicted. Photophysical properties of the complexes were studied by means of UV-visible absorption, and steady-state and time-resolved luminescence spectroscopy. Excited-state luminescence lifetimes of the complexes were determined in water and deuterated water to gain insight into the number of water molecules directly coordinated in the first coordination sphere of the complexes. The coordination behaviour of the series of ligands is questioned in the light of the spectroscopic data and discussed in terms of protection of the cation towards water molecules and their impact on the luminescence efficiency.
NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES
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Paragraph 0138, (2016/10/31)
Disclosed herein are 5 or 8-substituted imidazo[l,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[l,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8- substituted imidazo[l,5-a]pyridines that can be useful for inhibiting indoleamine 2,3- dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.
Synthesis and binding properties of guanidinium biscarboxylates
Spaeth, Andreas,Gonschor, Janina,Koenig, Burkhard
experimental part, p. 1289 - 1308 (2012/06/15)
The ammonium ion binding site of the enzyme glutaminase HisF inspired us to design guanidinium biscarboxylates as potential self-organized ionophores in molecular recognition. The syntheses of the title compounds based on aliphatic and aromatic building b
Dimeric self-assembly of pyridyl guanidinium carboxylates in polar solvents
Irfan Ashiq, Muhammad,Tesfatsion, Biniam F.,Gaggini, Francesca,Dixon, Sally,Kilburn, Jeremy D.
experimental part, p. 12387 - 12397 (2011/02/22)
A series of pyridyl guanidinium-carboxylates has been prepared and the dimeric self-assembly of these studied in H2O/DMSO mixtures, principally using dilution isothermal calorimetry. Compounds 5 and 6, incorporating an aromatic ring in the "tet
Functional Micellar Catalysis. Part 8. Catalysis of the Hydrolysis of p-Nitrophenyl Picolinate by Metal-chelating Micelles containing Copper(II) or Zinc(II)
Fornasier, Roberto,Milani, Daria,Scrimin, Paolo,Tonellato, Umberto
, p. 233 - 238 (2007/10/02)
The kinetic analysis of the esterolysis of p-nitrophenyl picolinate in neutral aqueous solutions of Cu2+ and Zn2+ in the presence of co-micelles made up of cetyltrimethylammonium bromide and either 6-(myristoylamido)methylpyridine-2-
