1041204-86-7

Basic information

• Product Name: 5-(2H-tetrazol-5-yl)biphenyl-3-carboxylic acid
• Synonyms: 5-(2H-tetrazol-5-yl)biphenyl-3-carboxylic acid;5-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-3-carboxylic acid
• CAS NO: 1041204-86-7
• Molecular Formula: C₁₄H₁₀N₄O₂
• Molecular Weight: 266.2548
• Mol File: 1041204-86-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(2H-tetrazol-5-yl)biphenyl-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2H-tetrazol-5-yl)biphenyl-3-carboxylic acid(1041204-86-7)
• EPA Substance Registry System: 5-(2H-tetrazol-5-yl)biphenyl-3-carboxylic acid(1041204-86-7)

Safety Data

• Hazardous Substances Data: 1041204-86-7(Hazardous Substances Data)

Upstream product

• 1041204-85-6 methyl 5-(tetrazol-5-yl)biphenyl-3-carboxylate 

Downstream Products

• 1041505-98-9 5-(4-oxo-1'-{[5-(tetrazol-5-yl)biphenyl-3-yl]carbonyl}-spiro[chroman-2,4'-piperidin]-6-yl)pyridine-3-carboxamide 
• 1041203-91-1 6-(1-methylethyl)-1'-{[5-(tetrazol-5-yl)biphenyl-3-yl]carbonyl}spiro[7-azachroman-2,4'-piperidin]-4-one 
• 1041203-92-2 6-(1-methyl-1H-pyrazol-4-yl)-1'-{[5-(tetrazol-5-yl)biphenyl-3-yl]carbonyl}spiro[chroman-2,4'-piperidin]-4-one 

Relevant articles and documents

SPIROCHROMANON DERIVATIVES

The invention relates to a compound of a general formula (I): wherein Ar1 represents a group formed from an aromatic ring selected from a group consisting of benzene, pyrazole, isoxazole, pyridine, indole, 1H-indazole, 1H-furo[2,3-c]pyrazole, 1H-thieno[2,3-c]pyrazole, benzimidazole, 1,2-benzisoxazole, imidazo[1,2-a]pyridine, imidazo[1,5-a]pyridine and 1H-pyrazolo[3,4-b]pyridine, having Ar2, and optionally having one or two or more substituents selected from R3; R1 and R2 each independently represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, an aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6 alkenyl group, or a group of -Q1-N(Ra)-Q2-Rb; or a C1-C6 alkyl group optionally having a substituent; or an aryl or heterocyclic group optionally having a substituent; or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclic group; T and U each independently represent a nitrogen atom or a methine group; and V represents an oxygen atom or a sulfur atom. The compound of the invention is useful as therapeutical agents for various ACC-related diseases.