104202-16-6

Basic information

• Product Name: 3-(4-nitrophenyl)imidazo[1,5-a]pyridine
• Synonyms: 3-(4-nitrophenyl)imidazo[1,5-a]pyridine
• CAS NO: 104202-16-6
• Molecular Formula: C13H9N3O2
• Molecular Weight: 239.23
• Mol File: 104202-16-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-nitrophenyl)imidazo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-nitrophenyl)imidazo[1,5-a]pyridine(104202-16-6)
• EPA Substance Registry System: 3-(4-nitrophenyl)imidazo[1,5-a]pyridine(104202-16-6)

Safety Data

• Hazardous Substances Data: 104202-16-6(Hazardous Substances Data)

Upstream product

• 274-47-5 imidazo[1,5-a]pyridine 
• 586-78-7 para-nitrophenyl bromide 
• 636-98-6 p-nitrobenzene iodide 

Relevant articles and documents

Direct sequential C3 and C1 arylation reaction of imidazo[1,5-a]pyridine catalyzed by a 1,10-phenanthrolinepalladium complex

The direct sequential arylation reaction at the C3 and C1 positions of imidazo[1,5-a]pyridines with a variety of aryl iodides catalyzed by [Pd(phen)2](PF6)2 is described. The reaction of unsubstituted imidazo[1,5-a]pyridine with various aryl iodides proceeded selectively at the C3 position to exclusively give the corresponding C3-arylated products. The one-pot double-arylation reaction at the C3 and C1 positions of unsubstituted imidazo[1,5-a]pyridine with different aryl groups was also achieved.

Palladium-catalyzed highly regioselective C-3 arylation of imidazo[1,5-a]pyridine

A direct palladium-catalyzed highly regioselective C-3 arylation of imidazo[1,5-a]pyridine with aryl bromides has been developed. This reaction is quite general with respect to the aryl or hetaryl bromide.