Direct ortho-arylation of 2-arylbenzoxazoles via C-H activation
A new and highly regioselective arylation of 2-arylbenzoxazoles based on C-H activation has been developed. The results represent the first examples of palladium-catalyzed direct ortho-arylation of 2-arylbenzoxazoles and also provide a facile route for the synthesis of complicated structures containing arylated benzoxazoles moieties.
Modified palladium-catalyzed regioselective ortho-arylation of sp2 C-H bond substrates with a low catalyst loading
A novel and generally applicable system for ortho-arylation of a broad range of sp2 C-H bond substrates such as arylated benzoxazoles, acylated anilines, and pyridines has been developed. The arylation was performed in trifluoroacetic acid (TFA