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104408-29-9

4-Hydrazino-2-(methylsulfanyl)pyrimidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 104408-29-9 Structure

  • Basic information

    1. Product Name: 4-Hydrazino-2-(methylsulfanyl)pyrimidine
    2. Synonyms: 4-Hydrazino-2-(methylsulfanyl)pyrimidine;4-Hydrazinyl-2-(methylsulfanyl)pyrimidine;4-Hydrazinyl-2-(methylthio)pyrimidine
    3. CAS NO:104408-29-9
    4. Molecular Formula: C5H8N4S
    5. Molecular Weight: 156.20882
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 104408-29-9.mol

  • Chemical Properties

    1. Melting Point: 143-145°
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-Hydrazino-2-(methylsulfanyl)pyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-Hydrazino-2-(methylsulfanyl)pyrimidine(104408-29-9)
    11. EPA Substance Registry System: 4-Hydrazino-2-(methylsulfanyl)pyrimidine(104408-29-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 104408-29-9(Hazardous Substances Data)

104408-29-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 104408-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,4,0 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 104408-29:
(8*1)+(7*0)+(6*4)+(5*4)+(4*0)+(3*8)+(2*2)+(1*9)=89
89 % 10 = 9
So 104408-29-9 is a valid CAS Registry Number.

104408-29-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-methylsulfanylpyrimidin-4-yl)hydrazine

1.2 Other means of identification

Product number -
Other names 2-methylthiopyrimidine-4-ylhydrazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104408-29-9 SDS

104408-29-9Relevant articles and documents

Development of amino-pyrimidine inhibitors of c-Jun N-terminal kinase (JNK): Kinase profiling guided optimization of a 1,2,3-benzotriazole lead

Palmer, Wylie S.,Alam, Muzaffar,Arzeno, Humberto B.,Chang, Kung-Ching,Dunn, James P.,Goldstein, David M.,Gong, Leyi,Goyal, Bindu,Hermann, Johannes C.,Hogg, J. Heather,Hsieh, Gary,Jahangir, Alam,Janson, Cheryl,Jin, Sue,Ursula Kammlott,Kuglstatter, Andreas,Lukacs, Christine,Michoud, Christophe,Niu, Linghao,Reuter, Deborah C.,Shao, Ada,Silva, Tania,Trejo-Martin, Teresa A.,Stein, Karin,Tan, Yun-Chou,Tivitmahaisoon, Parcharee,Tran, Patricia,Wagner, Paul,Weller, Paul,Wu, Shao-Yong

, p. 1486 - 1492 (2013)

A series of amino-pyrimidines was developed based upon an initial kinase cross-screening hit from a CDK2 program. Kinase profiling and structure-based drug design guided the optimization from the initial 1,2,3-benzotriazole hit to a potent and selective J

Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): Optimization for JNK potency and physicochemical properties

Gong, Leyi,Han, Xiaochun,Silva, Tania,Tan, Yun-Chou,Goyal, Bindu,Tivitmahaisoon, Parch,Trejo, Alejandra,Palmer, Wylie,Hogg, Heather,Jahagir, Alam,Alam, Muzaffar,Wagner, Paul,Stein, Karin,Filonova, Lubov,Loe, Brad,Makra, Ferenc,Rotstein, David,Rapatova, Lubica,Dunn, James,Zuo, Fengrong,Porto, Joseph Dal,Wong, Brian,Jin, Sue,Chang, Alice,Tran, Patricia,Hsieh, Gary,Niu, Linghao,Shao, Ada,Reuter, Deborah,Hermann, Johaness,Kuglstatter, Andreas,Goldstein, David

, p. 3565 - 3569 (2013/07/28)

A novel series of indole/indazole-aminopyrimidines was designed and synthesized with an aim to achieve optimal potency and selectivity for the c-Jun kinase family or JNKs. Structure guided design was used to optimize the series resulting in a significant potency improvement. The best compound (17) has IC50 of 3 nM for JNK1 and 20 nM for JNK2, with greater than 40-fold selectivity against other kinases with good physicochemical and pharmacokinetic properties.

Inhibitors of JNK

-

Page/Page column 40, (2011/02/26)

The invention relates to JNK inhibitors and corresponding methods, formulations, and compositions for inhibiting JNK and treating JNK-mediated disorders. The application discloses JNK inhibitors, as described below in Formula I: wherein p, q, Y′, r, Rsup

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