104478-95-7

Basic information

• Product Name: Carbamic acid, (4-amino-3-methylphenyl)-, methyl ester (9CI)
• Synonyms: Carbamic acid, (4-amino-3-methylphenyl)-, methyl ester (9CI)
• CAS NO: 104478-95-7
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 0
• Mol File: 104478-95-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (4-amino-3-methylphenyl)-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (4-amino-3-methylphenyl)-, methyl ester (9CI)(104478-95-7)
• EPA Substance Registry System: Carbamic acid, (4-amino-3-methylphenyl)-, methyl ester (9CI)(104478-95-7)

Safety Data

• Hazardous Substances Data: 104478-95-7(Hazardous Substances Data)

Upstream product

• 104478-90-2 methyl (3-methyl-4-nitrophenyl)carbamate 

Downstream Products

• 104479-04-1 C₁₄H₁₈N₄O₆ 

Relevant articles and documents

COMPOUNDS FOR INHIBITING TNIK AND MEDICAL USES THEREOF

The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.

Quinone Imine Route to Benzimidazol-2-ylcarbamates. Part 1. Synthesis of Open-chain and Cyclic 5-Acylamino Derivatives.

The synthesis of the N',N''-bismethoxycarbonyl-N-(4-acylaminophenyl)guanidines (4) and (7) is described.Oxidation of these with LTA has led to the benzimidazol-2-ylcarbamates. (8), (9) and (10) through a regiospecific cyclisation of quinone imine intermediates.If the acylamino group is part of a ring, the yield of benzimidazoles (15) increases with the size of the lactam ring.The direction of ring closure may be controlled by electronic and steric factors.