104519-26-8

Basic information

• Product Name: 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-benzothiazole
• CAS NO: 104519-26-8
• Molecular Formula: C₁₆H₁₉N₃S
• Molecular Weight: 285.4072
• Mol File: 104519-26-8.mol

Chemical Properties

• Boiling Point: 448.6°C at 760 mmHg
• Flash Point: 225.1°C
• Density: 1.2g/cm³
• Vapor Pressure: 3.07E-08mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-benzothiazole(104519-26-8)
• EPA Substance Registry System: 2-(4-butyl-3,5-dimethyl-1H-pyrazol-1-yl)-1,3-benzothiazole(104519-26-8)

Safety Data

• Hazardous Substances Data: 104519-26-8(Hazardous Substances Data)

Upstream product

• 615-21-4 1,3-benzothiazol-2-ylhydrazine 
• 1540-36-9 3-butylpentane-2,4-dione 

Relevant articles and documents

Mass Spectra of Some 2-(4'-Butyl-3',5'-dimethylpyrazol-1'-yl)-6-substituted Benzothiazoles

The fragmentation of the title compounds on electron impact has been studied and the major processes interpreted.The base peak invariably appears at + whose origin from the butyl chain has been traced with the help of metastable ion studies and accurate mass measurements.Loss of methyl cyanide, involving the decomposition of the pyrazole moiety, is observed only from the fragment ions.

Synthesis and Antiinflammatory Activity of Some 2-(4'-Butyl-3',5'-dimethylpyrazol-1'-yl)-6-substituted-benzothiazoles and 4-Butyl-1-(6'-substituted-2'-benzothiazolyl)-3-methylpyrazol-5-ols

A number of title compounds (II and III) have been synthesized by the condensation of 6-substituted-2-hydrazino-benzothiazoles (I) with 3-butylpentane-2,4-dione and ethyl α-(n-butyl)acetoacetate, respectively.Some of these compounds show significant antiinflammatory activity.