- Synthesis and structure-activity relationships of 1-aralkyl-4- benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent σ ligands
-
In the attempt to define more accurately structure-affinity relationships for σ1 and σ2 ligands, we synthesized and tested on σ subtype receptors a series of aralkyl derivatives of 4-benzylpiperidine, in which the effect of modificat
- Costantino, Luca,Gandolfi, Francesca,Sorbi, Claudia,Franchini, Silvia,Prezzavento, Orazio,Vittorio, Franco,Ronsisvalle, Giuseppe,Leonardi, Amedeo,Poggesi, Elena,Brasili, Livio
-
p. 266 - 273
(2007/10/03)
-
- [(benzodioxan, benzofuran or benzopyran) alkylamino] alkyl substituted guanidines
-
The present invention is concerned with vasoconstricive [(benzodioxan, benzofuran or benzopyran)alkylamino]alkyl substituted guanidines having the formula STR1 the pharmaceutically acceptable acid addition salts thereof, and the stereochemically isomeric
- -
-
-
- Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
-
Benzoxazol- and benzothiazolamine derivatives having anti-anoxic properties which compounds are useful in the treatment of anoxia. These compounds are produced from certain benzoxazol- and benzothizolamine intermediates.
- -
-
-
- Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
-
The invention relates to novel hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds of formula STR1 in which the variable R1, R2, R3, R4, R5, alk, X, Z, m, n and p, the dotted line and t
- -
-
-
- Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents
-
Benzoxazol-and benzothiazolamine derivatives having anti-anoxic properties which compounds are useful in the treatment of anoxia.
- -
-
-