Effective high-pressure cleavage of sterically hindered steroid esters
A simple and effective method to deprotect of sterically hindered steroid esters is described. Deprotection was carried out in MeOH in the presence of a catalytic amount of Et3N under high-pressure conditions. Enzymatic, anionite, and high-pressure methods are compared.
Kroszczynski, Wojciech,Olszewska, Ewa,Salanski, Piotr,Jurczak, Janusz