Synthesis of a New Class of Uridine Phoshorylase Inhibitors
A new series of potent uridine phosphorylase inhibitors have been prepared from barbituric acid.Among them 1--5-(m-benzyloxy)benzylbarbituric acid (37, BBBA) is the most promising having a Ki value of 1.1 +/- 0.2 nM wit
Tzeng, Cherng-Chyi,Panzica, Raymond P.,Naguib, Fardos N.M.,Kouni, Mahmoud H. el
p. 1399 - 1404
(2007/10/02)
Preparation of 5-substituted benzylbarburituric acids and investigation of the effect of the benzyl and substituted benzyl groups on the acidity of barbituric acid
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Tate,Tinnermann II,Jurevics,et al.
p. 9 - 11
(2007/10/02)
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