Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives
A series of 2-substituted amino-3-chloro-1,4-naphthoquinone derivatives (3-12) were synthesized as anticancer agents and tested against four cancer cell lines including HepG2, HuCCA-1, A549 and MOLT-3. The most potent cytotoxic activity against the HepG2,
INVESTIGATION IN THE AREA OF 1,4-NAPHTHOQUINONE. IX. SEMIDINE AND PROTOTROPIC REARRANGEMENTS IN THE REACTION OF 1,1-DIPHENYLHYDRAZINE WITH NAPHTHOQUINONES
The relative reactivity of the reaction centers of the naphthoquinonoid system was established for the case of the reactions of 1,1-diphenylhydrazine with 1,4-naphthoquinone and its 2-chloro-, 2,3-dichloro- and 5-hydroxy-substituted derivatives.The 1,1-di
Litvin, B. L.,Kolesnikov, V. T.,Kopel'tsiv, Yu. A.,Yarish, M. E.
p. 124 - 129
(2007/10/02)
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