Synthesis of β-hydroxy-α-amino acids with a reengineered alanine racemase
The Y265A mutant of alanine racemase (alrY265A) was evaluated as a catalyst for the synthesis of β-hydroxy-α-amino acids. It promotes the PLP-dependent aldol condensation of glycine with a range of aromatic aldehydes. The desired products were obtained wi
Fesko, Kateryna,Giger, Lars,Hilvert, Donald
supporting information; experimental part
p. 5987 - 5990
(2009/06/25)
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