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1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene, also known as TPE-MB, is an intermediate of aggregation-induced emission (AIE) material. It is a chemical compound with a unique structure that allows it to exhibit strong fluorescence in the aggregated state. This property makes it a promising candidate for various applications in different industries.

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  • 1053241-67-0 Structure
  • Basic information

    1. Product Name: 1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene
    2. Synonyms: 1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene
    3. CAS NO:1053241-67-0
    4. Molecular Formula: C28H22Br2
    5. Molecular Weight: 518.28228
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1053241-67-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 533.5±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.421±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene(1053241-67-0)
    11. EPA Substance Registry System: 1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene(1053241-67-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1053241-67-0(Hazardous Substances Data)

1053241-67-0 Usage

Uses

Used in Bio-imaging Applications:
1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene is used as an intermediate in the synthesis of blue mitochondrial dyes for bio-imaging. Its AIE properties enable the development of fluorescent probes that can selectively label and visualize mitochondria in living cells, providing valuable insights into cellular processes and disease mechanisms.
Used in Fluorescence Detection Applications:
1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene is used in the preparation of aggregation-induced emission (AIE) probes for the fluorescence detection of mercury(II) and glutathione. These AIE probes can selectively detect and quantify these analytes in complex samples, offering a sensitive and reliable method for environmental monitoring and biomedical research.
Used in Pharmaceutical Industry:
1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene may also be used in the development of new drugs and drug delivery systems. Its unique chemical structure and AIE properties can be exploited to design novel therapeutic agents and improve the efficiency of drug delivery, potentially leading to more effective treatments for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 1053241-67-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,3,2,4 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1053241-67:
(9*1)+(8*0)+(7*5)+(6*3)+(5*2)+(4*4)+(3*1)+(2*6)+(1*7)=110
110 % 10 = 0
So 1053241-67-0 is a valid CAS Registry Number.

1053241-67-0 Well-known Company Product Price

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  • Aldrich

  • (797332)  1,2-Bis[4-(bromomethyl)phenyl]-1,2-diphenylethene  

  • 1053241-67-0

  • 797332-25MG

  • 4,801.68CNY

  • Detail

1053241-67-0Relevant articles and documents

Synthesis of isoniazid-substituted tetraphenylethylene stereoisomers with dramatic differences on aggregate morphologies, optical and mechanocharomic properties

Lu, Zhixiang,Lu, Shuhan,Cheng, Yi,Qin, Yu,Yang, Shaoxiong,Liu, Xiaolan,Fan, Wenwen,Zheng, Liyan,Zhang, Hongbin

, (2020/02/15)

Stereoisomers play an irreplaceable prominent role in life sciences. In molecular engineering, the isomers have been continuously designed and synthesized, and their interrelationships among structure-property-function have also been explored. However, th

An Intracellular H2O2-Responsive AIEgen for the Peroxidase-Mediated Selective Imaging and Inhibition of Inflammatory Cells

Cheng, Yong,Dai, Jun,Sun, Chunli,Liu, Rui,Zhai, Tianyou,Lou, Xiaoding,Xia, Fan

, p. 3123 - 3127 (2018/02/26)

Inflammatory cells have gained widespread attention because inflammatory diseases increase the risk for many types of cancer. Therefore, it is urgent and important to implement detection and treatment methods for inflammatory cells. Herein, we constructed

Four styrene double crown ether and beryllium two pyrrole derivative of super-molecular self-assembly (by machine translation)

-

, (2017/07/22)

The present invention discloses a self-assembling ultra-molecular material, preparation method and its application. The invention to beryllium two pyrrole as the parent substance, its chemical structure has been modified with imine structure beryllium two

Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins

-

, (2016/04/20)

Compounds that exhibit aggregation induced emission (AIE), and more particularly to water-soluble conjugated polyene compounds that exhibit aggregation induced emission. The conjugated polyene compounds can be used as bioprobes for DNA detection, G-quadru

Photoswitchable aggregation-induced emission polymer containing dithienylethene and tetraphenylethene moieties

Sinawang, Garry,Wang, Jilei,Wu, Bing,Wang, Xiaogong,He, Yaning

, p. 12647 - 12651 (2016/02/18)

A photochromic aggregation-induced emission (AIE) active polymer containing dithienylethene (DTE) and tetraphenylethene (TPE) moieties was synthesized through a nucleophilic substitution reaction between 1,2-bis[5′-(4′′-hydroxyphenyl)-2′-ethylthien-3′-yl]

Water-dispersible nanospheres of hydrogen-bonded supramolecular polymers and their application for mimicking light-harvesting systems

Peng, Hui-Qing,Xu, Jiang-Fei,Chen, Yu-Zhe,Wu, Li-Zhu,Tung, Chen-Ho,Yang, Qing-Zheng

, p. 1334 - 1337 (2014/01/23)

Water-dispersible nanospheres of hydrogen-bonded supramolecular polymers have been prepared for the first time by using the miniemulsion method. Nanospheres containing chromophores with high fluorescence quantum yields were fabricated to mimic the natural

Distinct optical and kinetic responses from E/Z isomers of caspase probes with aggregation-induced emission characteristics

Liang, Jing,Shi, Haibin,Kwok, Ryan T. K.,Gao, Meng,Yuan, Youyong,Zhang, Wenhua,Tang, Ben Zhong,Liu, Bin

, p. 4363 - 4370 (2014/07/07)

A dual-labeled probe for monitoring caspase activity was designed and synthesized based on a tetraphenylethene (TPE) fluorogen with aggregation-induced emission characteristics and a caspase-specific Asp-Glu-Val-Asp (DEVD) peptide. Two stereoisomers were furnished and successfully separated by HPLC. We demonstrated for the first time the effect of isomerization on the reaction kinetics between the probes and caspase. It was revealed that caspase can produce a much higher light-up ratio for the Z-TPE-2DEVD probe, while its kinetics favor E-TPE-2DEVD due to enhanced probability of optimal binding between the two. Understanding the stereoisomers and their biological functions will open new opportunities for bioprobe design with optimized performance. This journal is the Partner Organisations 2014.

A photostable AIE luminogen for specific mitochondrial imaging and tracking

Leung, Chris Wai Tung,Hong, Yuning,Chen, Sijie,Zhao, Engui,Lam, Jacky Wing Yip,Tang, Ben Zhong

, p. 62 - 65 (2013/02/25)

Tracking the dynamics of mitochondrial morphology has attracted much research interest because of its involvement in early stage apoptosis and degenerative conditions. To follow this process, highly specific and photostable fluorescent probes are in deman

Luminogenic materials constructed from tetraphenylethene building blocks: Synthesis, aggregation-induced emission, two-photon absorption, light refraction, and explosive detection

Hu, Rongrong,Maldonado, Jose Luis,Rodriguez, Mario,Deng, Chunmei,Jim, Cathy K. W.,Lam, Jacky W. Y.,Yuen, Matthew M. F.,Ramos-Ortiz, Gabriel,Tang, Ben Zhong

, p. 232 - 240 (2013/01/12)

Luminogenic molecules [(TPE)3 (1), TPE-C = C-TPE-C = C-TPE (2), and TPE-C≡C-TPE-C≡C-TPE (3)] and their polymers P1-P3 are constructed from tetraphenylethene (TPE) building blocks in high yields by Suzuki, Witting, and Sonogashira coupling react

A new ratiometric Ag+ fluorescent sensor based on aggregation-induced emission

Ye, Jia-Hai,Duan, Lingjun,Yan, Congcong,Zhang, Whenchao,He, Weijiang

scheme or table, p. 593 - 596 (2012/02/02)

The novel tetraphenylethylene(TPE)-based sensor 1 bearing bis(2-pyridin-2-ylmethyl)amine (BPA) units linked with triazole moieties could be obtained by click reaction efficiently. The results show that 1 can demonstrate a Ag+-specific emission

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