105453-62-1

Basic information

• Product Name: (1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol
• CAS NO: 105453-62-1
• Molecular Formula: C₂₂H₁₆O₂
• Molecular Weight: 312.3612
• Mol File: 105453-62-1.mol

Chemical Properties

• Boiling Point: 606.1°C at 760 mmHg
• Flash Point: 289.5°C
• Density: 1.382g/cm³
• Vapor Pressure: 1.52E-15mmHg at 25°C
• Refractive Index: 1.831
• CAS DataBase Reference: (1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol(105453-62-1)
• EPA Substance Registry System: (1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol(105453-62-1)

Safety Data

• Hazardous Substances Data: 105453-62-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol is used as a building block in organic synthesis for constructing more complex molecules due to its unique structure and potential reactivity.
Used in Pharmaceutical Research:
(1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol is utilized in pharmaceutical research as a compound with potential applications in drug development, given its unique structure and properties.
Used in Material Science Research:
(1S,2S)-1,2-dihydrobenzo[k]tetraphene-1,2-diol is employed in material science research to explore its potential in creating new materials or improving existing ones, owing to its distinctive structural features and reactivity.

Upstream product

• 72378-83-7 1,4,7,8,11,14-Hexahydrodibenzanthracene 
• 57816-08-7 7,14-dihydrodibenz[a,h]anthracene 
• 66267-13-8 trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzanthracene 
• 79970-90-4 C₃₆H₂₅BrO₄ 
• 79970-86-8 1-acetoxy-1,2,3,4-tetrahydrodibenzanthracene 
• 79970-88-0 3,4-dihydrodibenzanthracene 
• 72390-46-6 1,2,3,4,7,8,9,10,11,14-decahydro-dibenz[a,h]anthracene 
• 153-39-9 1,2,3,4-tetrahydrodibenzanthracene 
• 53-70-3 dibenzo[a,h]anthracene 
• 66267-08-1 1,2-dihydrodibenzanthracen-4(3H)-one 
• 66302-72-5 trans-1,2-bis(benzoyloxy)-1,2-dihydrodibenzanthracene 
• 66267-18-3 trans-1,2-dihydroxy-1,2-dihydrodibenzanthracene 

Downstream Products

• 1421-82-5 (-)-(1R,2R)-1,2-dihydroxy-1,2-dihydrodibenz[a,h]anthracene 
• 79036-79-6 (1S,2R,3R,4R)-1,2,3,4-Tetrahydro-dibenzo[a,h]anthracene-1,2,3,4-tetraol 
• 79036-79-6 (1S,2R,3S,4R)-1,2,3,4-Tetrahydro-dibenzo[a,h]anthracene-1,2,3,4-tetraol 
• 79036-79-6 (1S,2R,3R,4S)-1,2,3,4-Tetrahydro-dibenzo[a,h]anthracene-1,2,3,4-tetraol 

Relevant articles and documents

Synthesis, absolute configuration, and bacterial mutagenicity of the 8 stereoisomeric vicinal diol epoxides at the terminal benzo ring of carcinogenic dibenz[ a,h ]anthracene

The synthesis of the 8 possible stereoisomeric diol epoxides (DEs) at the terminal benzo ring of carcinogenic dibenz[a,h]anthracene (DBA) is reported. trans-3,4-Dihydroxy-3,4-dihydro-DBA (1) afforded the 4 bay region DEs: the enantiomeric pairs of the ant

Synthesis of Biologically Active Metabolites of Dibenzanthracene

Syntheses are described of the trans 1,2- and 3,4-dihydro diol metabolites (3a and 1a) of dibenzanthracene (DBA) and the corresponding diol epoxide derivatives 4 and 2, implicated as the ultimate carcinogenic metabolites of DBA.The synheses of 1a and 3a are accomplished from DBA via lithium-ammonia reduction to 1,4,7,8,11,14-hexahydrodibenzanthracene, base-catalyzed isomerization, Prevost reaction, dehydrogenation, and basic methanolysis.This approach involves considerably fewer steps and affords superior overall yields than obtainable by more conventional methods entailing multistep ring construction.Epoxidation of 1a affords stereospecifically the anti diol epoxide isomer 2, whereas similar reaction of 3a furnishes a mixture of the corresponding syn and anti diol epoxide isomers in 3:1 ratio.Biological evidence implicates 1a and 2 as proximate and ultimate carcinogenic forms, respectively, of DBA.Synthesis of 3-hydroxydibenzanthracene, also known to be a metabolite of DBA, is also described.