We describe a novel series of imidazopyridine substituted phenylalanines which are potent VLA-4 antagonists. A wide variety of substituents are tolerated as replacements for the pendant 3-pyridyl ring. A clear structure-activity relationship was identifie
Phillips, David J.,Davenport, Richard J.,Demaude, Thierry A.,Galleway, Fiona P.,Jones, Mark W.,Knerr, Laurent,Perry, Benjamin G.,Ratcliffe, Andrew J.
scheme or table
p. 4146 - 4149
(2009/04/07)
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