105515-20-6

Basic information

• Product Name: 3'-BroMo-5'-fluoroacetophenone
• Synonyms: 3'-BroMo-5'-fluoroacetophenone;1-(3-broMo-5-fluorophenyl)ethanone
• CAS NO: 105515-20-6
• Molecular Formula: C₈H₆BrFO
• Molecular Weight: 217.0350432
• Mol File: 105515-20-6.mol

Chemical Properties

• Boiling Point: 257.9±25.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.535±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3'-BroMo-5'-fluoroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-BroMo-5'-fluoroacetophenone(105515-20-6)
• EPA Substance Registry System: 3'-BroMo-5'-fluoroacetophenone(105515-20-6)

Safety Data

• Hazardous Substances Data: 105515-20-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Research:
3'-BroMo-5'-fluoroacetophenone is used as an intermediate in organic synthesis for chemical research. Its stable nature, ability to transform, and reactivity with different reagents make it a valuable compound for creating new organic molecules and studying their properties.
Used in Pharmaceutical Industry:
3'-BroMo-5'-fluoroacetophenone is used as a building block in the synthesis of pharmaceutical compounds. Its unique combination of bromine and fluorine atoms, along with its ketone group, can contribute to the development of new drugs with potential therapeutic applications.
Used in Material Science:
3'-BroMo-5'-fluoroacetophenone is used as a precursor in the development of new materials with specific properties. Its reactivity and structural features can be exploited to create materials with tailored characteristics for various applications, such as in electronics or advanced materials.

Upstream product

• 1435-51-4 1,3-dibromo-5-fluorobenzene 
• 78191-00-1 N-Methoxy-N-methylacetamide 
• 176548-70-2 3-bromo-5-fluorobenzoic acid 
• 627527-04-2 1-(3-bromo-5-fluorophenyl)ethanol 

Downstream Products

• 1180016-23-2 (RS)-1-(3-Bromo-5-fluorophenyl)-1-(4-methoxy-3-methylphenyl)-ethanol 
• 627526-99-2 1-bromo-3-(1,1-difluoroethyl)-5-fluorobenzene 

Relevant articles and documents

Copper-Mediated Fluorination of Aryl Trisiloxanes with Nucleophilic Fluoride

A method for the nucleophilic fluorination of heptamethyl aryl trisiloxanes to form fluoroarenes is reported. The reaction proceeds in the presence of Cu(OTf)2 and KHF2 as the fluoride source under mild conditions for a broad range of heptamethyltrisiloxyarenes with high functional group tolerance. The combination of this method with the silylation of aryl C?H bonds enables the regioselective fluorination of non-activated arenes controlled by steric effects following a two-step protocol.

INTEGRIN ANTAGONISTS

The present disclosure provides pharmaceutical agents, including those of the formula:(I) wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such pharmaceutical agents. Meth

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Compounds of the formula I or a pharmaceutically acceptable salt thereof: processes for their preparation, pharmaceutical compositions which contain them and their uses in therapy.

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