Acylaminoacetyl Derivatives of Active Methylene Compounds. 2. The Cyclization of the Acetylaminoacetyl Derivatives to α-Substituted Tetramic Acids and the Formation of N-Acetyl-α-substituted Tetramic Acids
The reaction of aceturic acid p-nitrophenyl ester with active methylene compounds Y-CH2-CO2R has been found to give either the normally expected C-acylation compounds 2 (Y = -CN, -CO2R, -COCH3) or N-acetyl-α-Y-substituted tetramic acids 3 (Y = -CO2R, -COC
Igglessi-Markopoulou, Olga,Sandris, Constantine
p. 1599 - 1606
(2007/10/02)
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