An environmentally friendly synthesis of michlers ketone analogues in water
An environmentally friendly method for the synthesis of a series of novel, unsymmetrical Michlers ketone analogues, [4-(dialkylamino)phenyl](aryl) methanones, via nucleophilic aromatic substitution of (fluorophenyl)(aryl) methanones with various amines in water- is described. The reaction products are formed in high yields and additional purification is not required. The aqueous solvent and unreacted amines can be recycled. Georg Thieme Verlag Stuttgart · New York.
Shirinian, Valerii Z.,Shimkin, Alexey A.,Lonshakov, Dmitry V.,Mailyan, Artur K.,Lvov, Andrey G.,Krayushkin, Michail M.
experimental part
p. 527 - 531
(2012/04/17)
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