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N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 105746-37-0 Structure
  • Basic information

    1. Product Name: N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine
    2. Synonyms: N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine
    3. CAS NO:105746-37-0
    4. Molecular Formula: C19H27NO3
    5. Molecular Weight: 317.42258
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 105746-37-0.mol
  • Chemical Properties

    1. Melting Point: 230-232 °C
    2. Boiling Point: 527.6±39.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.104±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 3.61±0.10(Predicted)
    10. CAS DataBase Reference: N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine(105746-37-0)
    12. EPA Substance Registry System: N-(Trans-4-Isopropylcyclohexylcarbonyl)-D-Phenyl Alanine(105746-37-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 105746-37-0(Hazardous Substances Data)

105746-37-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 105746-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,7,4 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 105746-37:
(8*1)+(7*0)+(6*5)+(5*7)+(4*4)+(3*6)+(2*3)+(1*7)=120
120 % 10 = 0
So 105746-37-0 is a valid CAS Registry Number.

105746-37-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name nateglinide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:105746-37-0 SDS

105746-37-0Upstream product

105746-37-0Downstream Products

105746-37-0Relevant articles and documents

COMPOSITIONS AND METHODS FOR THE TREATMENT OF DIABETES

-

, (2016/06/01)

The invention relates to the compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of fo

Synthesis and biological investigations of nitric oxide releasing nateglinide and meglitinide type II antidiabetic prodrugs: In-vivo antihyperglycemic activities and blood pressure lowering studies

Kaur, Jatinder,Bhardwaj, Atul,Huang, Zhangjian,Narang, Deepak,Chen, Ting-Yueh,Plane, Frances,Knaus, Edward E.

, p. 7883 - 7891 (2012/11/07)

A new group of hybrid nitric oxide-releasing type II antidiabetic drugs possessing a 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (13 and 18), 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate (14 and 19), or nitrooxyethyl (15 and 20) moiety attached to the car

PROCESS FOR PRODUCTION OF CARBOXYLIC ACID CHLORIDE COMPOUND

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Page/Page column 8, (2009/01/24)

The present invention discloses methods for producing a carboxylic acid chloride compound which comprises the step of reacting an alkyl-substituted cyclohexyl carboxylic acid with a chlorinating agent in the presence of a specific urea compound. According to this invention, it is possible to produce a carboxylic acid chloride compound which has high reaction speed, and whose product has high purity or high yield. Thus produced carboxylic acid chloride compound is useful as an intermediate for producing D-phenylalanine derivatives which are used as agents for treating diabetes.

PROCESS FOR SYNTHESIZING HIGHLY PURE NATEGLINIDE POLYMORPHS

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Page/Page column 15-16, (2008/12/08)

The present invention relates to an improved process for synthesizing highly pure nateglinide of formula-(I). More particularly, the present invention relates to the process for synthesizing highly enantiomerically pure nateglinide form B and form H direc

PROCESS FOR PREPARING NATEGLINIDE B-TYPE CRYSTALS

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Page/Page column 11-12, (2008/06/13)

An improved process for preparing (-)-N-[(trans-4-isopropylcyclohexane)carbonyl]-D-phenylalanine of Formula I.

Process for the preparation of nateglinide, preferably in B-form

-

Page/Page column 5; 6, (2008/06/13)

The present invention relates to a process for the preparation of nateglinide, preferably in B-form, substantially free from the H-form, comprising three steps starting from D-phenylalanine methyl ester or a salt thereof.

CRYSTALLINE FORM OF NATEGLINIDE AND PROCESS FOR PREPARATION THEREOF

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Page 19, (2008/06/13)

A new crystalline form of nateglinide (N-(trans-4-isopropylcyclohexanecarbonyl)D-phenylalanine) is provided. The new crystalline form is described by X-ray owder diffraction. Process for making the new crystalline form of nateglinide a e also provided.

NOVEL FORM OF N-(TRANS-4-ISOPROPYLCYCLOHEXYLCARBONYL)-D-PHENYLALANINE

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Page/Page column 7-8, (2010/02/07)

Novel polymorph Form C of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine is produced having different infra red spectrum and X-ray diffraction patterns from previously known forms of the compound.

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