105851-18-1

Basic information

• Product Name: 2-[18F]Fluoro-2-deoxy-β-D-glucopyranose
• CAS NO: 105851-18-1
• Molecular Formula: C₆H₁₁FO₅
• Molecular Weight: 0
• Mol File: 105851-18-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[18F]Fluoro-2-deoxy-β-D-glucopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[18F]Fluoro-2-deoxy-β-D-glucopyranose(105851-18-1)
• EPA Substance Registry System: 2-[18F]Fluoro-2-deoxy-β-D-glucopyranose(105851-18-1)

Safety Data

• Hazardous Substances Data: 105851-18-1(Hazardous Substances Data)

Upstream product

• 84243-95-8 1,3,4,6-tetra-O-acetyl-2-deoxy-2-<18F>fluoro-D-mannopyranose 
• 128441-61-2 1,3,4,6-tetra-O-acetyl-2-deoxy-2-<18F>fluoro-D-glucopyranose 
• 92051-23-5 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose 
• 105285-83-4 2-deoxy-2-[⁽¹⁸⁾F]fluoro-1,3,4,6-tetra-O-acetyl-D-glucose 
• 84766-01-8 1,2-anhydro-3,4:5,6-di-O-isopropylidene-1-C-nitro-D-mannitol 
• 110824-72-1 C₁₄H₁₉⁽¹⁸⁾FO₉ 
• 21193-75-9 D-galactal 
• 94715-29-4 2-deoxy-2-<18F>fluoro-3,4:5,6-di-O-isopropylidene-aldehydo-D-glucose 
• 13265-84-4 D-glucal 
• 67470-60-4 3,4,6-tri-O-acetyl-2-deoxy-2-<18F>fluoro-α-D-glucopyranosyl <18F>fluoride 
• 67470-61-5 3,4,6-tri-O-acetyl-2-deoxy-2-<18F>fluoro-β-D-mannopyranosyl <18F>fluoride 

Downstream Products

• 63503-12-8 [18F]-Fluorodeoxyglucose 

Relevant articles and documents

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ELUENT SOLUTION

The present invention provides a novel method for the preparation of 18F-fluoride (18F) for use in radiofluorination reactions. The method of the invention finds use especially in the preparation of 18F-labelled positron emission tomography (PET) tracers. The method of the invention is particularly advantageous where bulk solutions are prepared and stored in prefilled vials rather than being freshly prepared on the day of synthesis. Also provided by the present invention is a radiofluorination reaction which comprises the method of the invention, as well as a cassette for use in carrying out the method of the invention and/or the radiofluorination method of the invention on an automated radiosynthesis apparatus.