Investigations on local anaesthetics, IC: Syntheses and local anaesthetic properties of alkoxyphenylcarbamates
Within the framework of studying the influence of alterations of the connecting chain in the group of local anaesthetics a series of 24 compounds of 1-propoxymethyl-2-(1-pyrrolidinyl), 2-(1-piperidino)-, and 2-(1-perhydroazepinyl)-ethyl esters of o- and m-alkoxyphenylcarbamic acid were prepared. Studied compounds show a high index of relative local anaesthetic activityas compared to the standards cocaine and procaine, at a relatively low acute toxicity.
Buciova,Csollei,Racanska,Svec
p. 393 - 396
(2007/10/02)
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