- 98. A Regioselective Cyclohexannulation Procedure via Dienamine Cycloaddition. Synthesis of Functionalised Decalins
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A regioselective cyclohexannulation procedure, whose key step involves the cycloaddition of dienamines 12-24 with methyl acrylate, allows the conversion of cycloalkanones 1-11 to bicyclic dienoates 25-37.The chemistry of 26 is briefly examined and, in the context of organoleptic studies concerning functionalised 5,5,9-trimethyldecalins, the transformation of 37 to ketones 44 and 46 as well as to acetates 53-56 is described.
- Snowden, Roger L.,Linder, Simon M.,Wuest, Manfred
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p. 892 - 905
(2007/10/02)
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- DIENAMINES AS DIELS-ALDER DIENES. AN EFFICIENT CYCLOHEXANNULATION SEQUENCE.
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An efficient cyclohexannulation sequence is described whose key step involves a Diels-Alder reaction between an (E)-dienamine and methyl acrylate.
- Snowden, Roger L.,Wuest, Manfred
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p. 699 - 702
(2007/10/02)
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