- Novel aminopeptidase N inhibitors derived from 1,3,4-thiadiazole scaffold
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The aminopeptidase N (APN/CD13), overexpressed in tumor cells, plays a critical role in angiogenesis. In this study, we report the synthesis and in vitro enzyme inhibition assay of 1,3,4-thiadiazole scaffold compounds. These new compounds have potent inhi
- Tu, GuoGang,Li, ShaoHua,Huang, HuiMing,Li, Gang,Xiong, Fang,Mai, Xi,Zhu, HuaWei,Kuang, BinHai,Xu, Wen Fang
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p. 6663 - 6668
(2008/12/22)
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