106265-07-0 Usage
Uses
Used in Organic Synthesis:
2-Bromo-2-methylbutanoyl bromide is employed as a reagent in organic synthesis, where it is utilized for the preparation of various organic compounds. Its high reactivity and ability to undergo nucleophilic substitution reactions make it an important tool for the introduction of the bromine functional group into organic molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 2-Bromo-2-methylbutanoyl bromide is used as an alkylating agent in chemical reactions. Its role in the synthesis of pharmaceuticals is crucial, as it aids in the modification of organic molecules, contributing to the development of new drugs and therapeutic agents.
Used in Research and Development:
2-Bromo-2-methylbutanoyl bromide is an important intermediate in the synthesis of various organic compounds, making it a key component in the research and development of new chemical entities. Its versatility in chemical reactions and its role in the creation of complex organic structures are essential for advancing the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 106265-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,2,6 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 106265-07:
(8*1)+(7*0)+(6*6)+(5*2)+(4*6)+(3*5)+(2*0)+(1*7)=100
100 % 10 = 0
So 106265-07-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H8Br2O/c1-3-5(2,7)4(6)8/h3H2,1-2H3
106265-07-0Relevant articles and documents
The synthetic protocol for α-bromocarbonyl compounds via brominations
Murata, Yumi,Takeuchi, Kentaro,Nishikata, Takashi
, p. 2726 - 2736 (2019)
α-Bromocarbonyl compound easily generates α-radicals in the presence of a proper initiator, such as copper salt. Recently, tertiary-alkylation reaction using α-bromocarbonyl compound as a tertiary alkyl source is recognized as one of the most important alkylation reactions. The reactions using α-bromocarbonyl compound are increasing, whereas synthetic methods for various functionalized α-bromocarbonyl compounds are not summarized. Generally, α-bromocarbonyl compounds can be synthesized from the corresponding carboxylic acids via α-bromo acid bromide, but the brominations of carboxylic acids are sometimes problematic. In this paper, we will report some technical information for a bromination and synthetic examples of representative α-bromocarbonyl compounds.
Iron-Catalyzed 1,4-Phenyl Migration/Ring Expansion of α-Azido N-Phenyl Amides
Wei, Kaijie,Liang, Siyu,Yang, Tonghao,Yu, Wei
supporting information, p. 8650 - 8654 (2021/11/13)
Herein, we report a novel iron-catalyzed skeleton rearrangement of alkyl azides. Upon treatment with FeCl2 and N-heterocyclic carbene SIPr·HCl in the presence of H2O and Et3N, 2-azido-N,N-diphenylamides underwent 1,4-phenyl migration and ring expansion to give azepin-2-ones in good yield. The reaction proceeds via intramolecular nitrene cycloaddition followed by C-N cleavage, water addition, and electrocyclic ring opening.
