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4-(Naphthalen-2-yl)benzoic acid, also known as 2-naphthoylbenzoic acid, is a chemical compound with the molecular formula C18H12O2. It features a naphthalene group attached to a benzoic acid group, and is recognized for its applications as a fluorescent probe, as well as its potential use in organic electronic devices and as a precursor in the synthesis of pharmaceuticals and agrochemicals. The unique structure and properties of this molecule contribute to its value in research and industrial applications across various fields such as medicine, materials science, and chemistry.

106359-70-0

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106359-70-0 Usage

Uses

Used in Research Applications:
4-(Naphthalen-2-yl)benzoic acid is used as a fluorescent probe for detecting structural changes in proteins, which is crucial for understanding protein dynamics and interactions in biological systems.
Used in Organic Electronic Devices:
4-(Naphthalen-2-yl)benzoic acid is utilized in the development of organic electronic devices due to its electronic properties, contributing to advances in flexible electronics and other related technologies.
Used as a Precursor in Pharmaceutical and Agrochemical Industries:
4-(Naphthalen-2-yl)benzoic acid serves as a precursor in the synthesis of various pharmaceuticals and agrochemicals, playing a key role in the production of new and existing drugs and pesticides.
Used in Material Science:
Its unique structure and properties make 4-(Naphthalen-2-yl)benzoic acid a valuable molecule for research in material science, where it can be employed to develop new materials with specific characteristics for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 106359-70-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,3,5 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 106359-70:
(8*1)+(7*0)+(6*6)+(5*3)+(4*5)+(3*9)+(2*7)+(1*0)=120
120 % 10 = 0
So 106359-70-0 is a valid CAS Registry Number.

106359-70-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-naphthalen-2-ylbenzoic acid

1.2 Other means of identification

Product number -
Other names 4-Naphthalen-2-yl-benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:106359-70-0 SDS

106359-70-0Relevant articles and documents

A general palladium-catalyzed cross-coupling of aryl fluorides and organotitanium (IV) reagents

He, Xiao-Yun

, p. 823 - 832 (2021/07/19)

Pd(OAc)2/1-[2-(di-tert-butylphosphanyl)phenyl]-4-methoxy-piperidine was demonstrated to effectively catalyze cross-coupling of aryl fluoride and aryl(alkyl) titanium reagent. Both electron-deficient and electron-rich aryl fluoride can react effectively with nucleophile and provide extensive functional groups tolerance. 2-Arylated product was realized by selective activation of the C–F bond. Graphic abstract: [Figure not available: see fulltext.].

Decarbonylative Phosphorylation of Carboxylic Acids via Redox-Neutral Palladium Catalysis

Liu, Chengwei,Ji, Chong-Lei,Zhou, Tongliang,Hong, Xin,Szostak, Michal

, p. 9256 - 9261 (2019/11/19)

We describe the direct synthesis of organophosphorus compounds from ubiquitous aryl and vinyl carboxylic acids via decarbonylative palladium catalysis. The catalytic system shows excellent scope and tolerates a wide range of functional groups (>50 examples). The utility of this powerful methodology is highlighted in the late-stage derivatization directly exploiting the presence of the prevalent carboxylic acid functional group. DFT studies provided insight into the origin of high bond activation selectivity and P(O)-H isomerization pathway.

One-step highly selective borylation/Suzuki cross-coupling of two distinct aryl bromides in pure water

Xu, Shan Dong,Sun, Fang Zhou,Deng, Wei Hang,Hao, Han,Duan, Xin Hong

supporting information, p. 16464 - 16468 (2018/10/24)

A Na2PdCl4-catalysed B2(OH)4-mediated direct cross-coupling of two distinct aryl bromides in pure water is described. This one-step borylation/Suzuki method exhibits an outstanding cross-coupling selectivity and no tendency to produce homocoupling products, therefore leading to biaryls and heterobiaryls in moderate to good yields. Moreover, the reaction has high regio-selectivity and can be scaled-up. Using such a simple, economical and practical protocol, the unsymmetrical diarylation of 3,5-dibromopryidine is achieved.

Method for synthesis of peptide using a carrier

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Page/Page column 26, (2016/04/05)

Disclosed are a carrier for use for separation purpose and a method for separation of a compound which enable a chemical reaction to be performed in a liquid phase, enable a compound of interest to be separated from the liquid phase after the completion of the reaction readily, enable the separated compound to be evaluated by structural analysis or the like while the compound being bound to the carrier, and enable the compound to be separated from the carrier readily. A carrier for separation which has a reaction site capable of reacting with other compound on a benzene ring, and a long-chain group having a specified carbon atom(s) at each of the ortho-position and the para-position of the reaction site through an oxygen atom.

PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERSAS AS AGONISTS OF G- PROTEIN COUPLED RECEPTOR 43 (GPR43)

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Page/Page column 203, (2011/07/07)

The present invention is directed to novel compounds of formula (I) and their use in treating and/or preventing metabolic diseases.

The 1,3-diaminobenzene-derived aminophosphine palladium pincer complex {C6H3[NHP(piperidinyl)2]2Pd(Cl)} - A highly active Suzuki-Miyaura catalyst with excellent functional group tolerance

Bolliger, Jeanne L.,Frech, Christian M.

experimental part, p. 1075 - 1080 (2010/06/17)

The rapidly prepared 1,3-diaminobenzenederived aminophosphine pincer complex {C6H3 [NHP(piperidinyl)2] 2Pd(Cl)} (1) is an effective Suzuki catalyst with excellent functional group tolerance. Side-product formations, such as homocoupling, debromation or protodeboration have only rarely been detected and if so, were in all cases below the 5% level. The presented reaction protocol is universally applicable. Experimental observations indicate that palladium nanoparticles are the catalytically active form of 1.

Novel and potent small-molecule urotensin II receptor agonists

Lehmann, Fredrik,Currier, Erika A.,Clemons, Bryan,Hansen, Lars K.,Olsson, Roger,Hacksell, Uli,Luthman, Kristina

supporting information; experimental part, p. 4657 - 4665 (2009/12/06)

A series of analogs of the non-peptidic urotensin II receptor agonist N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-4-phenylbenzamide (FL104) has been synthesized and evaluated pharmacologically. The enantiomers of the two most potent racemic analogues were obtained from the corresponding diastereomeric mandelic amides. In agreement with previously observed SAR, most of the agonist potency resided in the (S) enantiomers. The most potent UII receptor agonist in the new series was (S)-N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(4-chlorophenyl)benzamide (EC50 = 23 nM at the urotensin II receptor).

UII-MODULATING COMPOUNDS AND THEIR USE

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Page/Page column 42; 44, (2008/12/05)

Disclosed herein are novel aromatic-containing compounds and methods for using various aromatic-containing compounds for treatment and prevention of diseases and disorders related to the Urotensin II receptor.

CARRIER FOR SEPARATION, METHOD FOR SEPARATION OF COMPOUND, AND METHOD FOR SYNTHESIS OF PEPTIDE USING THE CARRIER

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Page/Page column 31-33, (2010/11/26)

Disclosed are a carrier for use for separation purpose and a method for separation of a compound which enable a chemical reaction to be performed in a liquid phase, enable a compound of interest to be separated from the liquid phase after the completion o

Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework

Ohnmacht, Stephan A.,Brenstrum, Tim,Bleicher, Konrad H.,McNulty, James,Capretta, Alfredo

, p. 5661 - 5663 (2007/10/03)

The use of a catalyst system based on Pd2dba3· CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha- adamantane allows for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.

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