106428-06-2Relevant articles and documents
PIPERIDINE DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF
-
Paragraph 0101; 0108; 0352; 0353, (2018/05/03)
The present invention relates to a piperidine derivative and the preparation method and a pharmaceutical use thereof. In particular, the present invention relates to the piperidine derivative as shown by general formula (I) and the preparation method thereof and a pharmaceutical composition containing same, and the use thereof as an estrogen receptor modulator in the treatment of estrogen receptor mediated or dependent diseases or conditions, the diseases particularly preferably being breast cancer. In the abstract, the definition of each substituent of the general formula (I) is the same as that in the description.
Pharmaceutical compositions
-
, (2008/06/13)
The invention concerns novel pharmaceutical compositions containing a 4(Z)-6-(2,4-diphenyl-1,3-dioxan-5-yl)-alkenoic acid which antagonizes one or more of the actions of thromboxane A2, together with a compound which inhibits the synthesis of t
2,4-diphenyl-1,3-dioxanes
-
, (2008/06/13)
The invention provides a novel group of 4(Z)-([2,4,5-cis]-2,4-diphenyl-1,3-dioxan-5-yl)hexenoic acids of formula I, wherein X is F, Cl, Br, CF3, CN, CH3 O or NO2 and one of Y and Z is hydrogen or fluoro and the other is hy