- Methyl-triflate-mediated dearylmethylation of: N -(arylmethyl)carboxamides via the retro-Mannich reaction induced by electrophilic dearomatization/rearomatization in an aqueous medium at room temperature
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We have developed a protocol for the dearylmethylation of N-(arylmethyl)carboxamides under metal-free conditions in an aqueous medium at room temperature. This protocol involves methyl triflate-mediated successive C-C and C-N bond cleavages (retro-Mannich reaction) induced by electrophilic dearomatization/rearomatization. The dearomatization/rearomatization strategy can be expected to inspire the development of novel transformations based on the C-C bond cleavage in an environmentally benign manner.
- Peng, Hui,Ma, Jinhui,Luo, Wenkun,Zhang, Guangwen,Yin, Biaolin
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Read Online
- Efficient microwave-assisted solvent-free synthesis of N-substituted aldimines
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Neat non-volatile amines react with various aromatic aldehydes in the absence of any catalyst, solid support, or solvent, to give imines after a reaction time of eight minutes under microwave irradiation by a clean and very efficient process (yields: 75-100%). In the case of volatile amine, methylamine, 1,3-dimethylurea dispersed on montmorillonite K10 is used as an amine precursor to prepare the corresponding imines. Georg Thieme Verlag Stuttgart.
- Paquin, Ludovic,Hamelin, Jack,Texier-Boullet, Francoise
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Read Online
- Fluorometric sensing of Hg2+ ions in aqueous medium by nano-aggregates of a tripodal receptor
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Two new tripodal receptors (1-2) have been synthesized and characterized by various spectroscopic techniques. The nano-aggregates of 1 and 2 (N1 and N2) have been prepared by a re-precipitation method in aqueous medium and have shown different photo-physi
- Singh, Ajnesh,Kaur, Simanpreet,Singh, Narinder,Kaur, Navneet
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p. 2302 - 2309
(2014/04/03)
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- Development of chemosensor for Sr2+ using organic nanoparticles: Application of sensor in product analysis for oral care
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A new series of compounds has been developed for the recognition of metal ions and it was found that the position of substituent in the organic compound proved to be the deciding factor for the development of a chemosensor. Reprecipitation method was used
- Kaur, Simanpreet,Kaur, Amanpreet,Kaur, Navneet,Singh, Narinder
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p. 8230 - 8238
(2015/01/08)
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- Novel caffeic acid amide antioxidants: Synthesis, radical scavenging activity and performance under storage and frying conditions
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Twelve novel dihydro-caffeic acid amides were synthesised in good yields and fully characterised by 1H NMR, 13C NMR, and MS. Their radical scavenging activities were assessed by DPPH assay. Additionally, their abilities to protect polyunsaturated oils under accelerated storage and frying conditions were evaluated. All the new compounds possessed significantly higher radical scavenging activities than α-tocopherol and butylated hydroxytoluene (BHT). The radical scavenging activity of N-decyl-N-(3,5- dimethoxy-4-hydroxybenzyl)-3-(3,4-dihydroxyphenyl) propanamide was 1.7 and 4 times higher than α-tocopherol and BHT, respectively. At the end of the storage period, the respective amounts of hydroperoxides in canola oil triacylglycerols (CTAG) fortified with α-tocopherol and BHT was 6.1 and 1.4 times higher, respectively, than CTAG containing the amide. The frying test showed that CTAG containing N-decyl-N-benzyl-3-(3,4-dihydroxybenzyl) propanamide was 1.3, 1.4, and 1.6 times more stable compared to oil fortified with dihydro-caffeic acid, α-tocopherol and BHT, respectively, as assessed by the amounts of the total polar compounds. Moreover, these compounds were remarkably thermally stable, making them suitable for frying applications.
- Aladedunye, Felix,Catel, Yohann,Przybylski, Roman
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experimental part
p. 945 - 952
(2012/05/05)
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- Efficient synthesis of new 4-arylideneimidazolin-5-ones related to the GFP chromophore by 2+3 cyclocondensation of arylideneimines with imidate ylides
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A 2+3 condensation of a wide assortment of Schiff bases, prepared from aromatic aldehydes and primary amines, with methyl (1-ethoxyethylideneamino) acetate allows convenient access to an extensive family of substituted 4-arylideneimidazolin-5-one analogues of the green fluorescent protein (GFP) chromophore. Georg Thieme Verlag Stuttgart · New York.
- Baldridge, Anthony,Kowalik, Janusz,Tolbert, Laren M.
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scheme or table
p. 2424 - 2436
(2010/09/06)
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- Separation of Ring Polar and Resonance Effects on the Rate Constants for Uncatalyzed N-Arylidenepropylamine Formation in Methanol
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Rate constants are reported for the reaction of a series of 19 ring-substituted benzaldehydes with propylamine in methanol and in O-d-methanol at different temperatures and of three of them with 2-methoxyethylamine and 2,2-dimethoxyethylamine.The large di
- Toullec, Jean,Milin, Didier
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p. 2840 - 2847
(2007/10/02)
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- Synthesis and Bleaching Activity of 1,5-Disubstituted Imidazoles
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A variety of 1,5-disubstituted imidazoles and related compounds were prepared, and their bleaching activity was evaluated by using the lettuce seedling test. 5-(4-Benzyloxyphenyl)-1-ethylimidazole (13) caused clear chlorosis, while the 2- and 3-benzyloxyp
- Yamada, Naotaka,Kuwano, Eiichi,Kikuchi, Masamichi,Eto, Morifusa
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p. 1943 - 1948
(2007/10/02)
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