106584-14-9Relevant articles and documents
Synthesis of complex fused polycyclic heterocycles utilizing IMDAF reactions of allylamino- or allyloxy-furyl(hetero)arenes
Read, Matthew L.,Krapp, Andreas,Miranda, Pedro O.,Gundersen, Lise-Lotte
experimental part, p. 1869 - 1885 (2012/03/26)
Arenes and heteroarenes carrying a halogen and an amino- or hydroxy group have been converted to allylamino- or allyloxy-furyl-(hetero)arenes. These compounds underwent IMDAF reactions to give complex fused polycyclic heterocycles. The reactivity of the s
The synthesis of 3-hydroxymethylfuro[3,2-b]naphtho[2,3-d]furan-5,10-dione, a novel metabolite isolated from Crescentia cujete
Nielsen, Linda B.,Slamet, Riskiono,Wege, Dieter
experimental part, p. 4569 - 4577 (2009/10/02)
The title natural product 1, which possesses a new ring skeleton, has been synthesised by a sequence in which the key steps involve a tandem intramolecular Diels-Alder/reverse Diels-Alder reaction sequence. Thus 3-(2-furyl)-1,4-dimethoxynaphthalen-2-ol wa
α1-Adrenoceptor agonists: The identification of novel α1A subtype selective 2′-heteroaryl-2-(phenoxymethyl)imidazolines
Bishop, Michael J.,Barvian, Kevin A.,Berman, Judd,Bigham, Eric C.,Garrison, Deanna T.,Gobel, Michael J.,Hodson, Stephen J.,Irving, Paul E.,Liacos, James A.,Navas, Iii, Frank,Saussy Jr., David L.,Speake, Jason D.
, p. 471 - 475 (2007/10/03)
Novel 2′-heteroaryl-2-(phenoxymethyl)imidazolines have been identified as potent agonists of the cloned human α1-adrenoceptors in vitro. The nature of the 2′-heteroaryl group can have significant effects on the potency, efficacy, and subtype selectivity in this series. α1A Subtype selective agonists have been identified.
Chromium- and tungsten-triggered valence isomerism of cis-1-acyl-2-ethynylcyclopropanes via [3,3] sigmatropy of (2-acylcyclopropyl)vinylidene - Metal intermediates
Ohe, Kouichi,Yokoi, Tomomi,Miki, Koji,Nishino, Fumiaki,Uemura, Sakae
, p. 526 - 527 (2007/10/03)
The reaction of cis vicinal acetylethynylcyclopropanes 1 with a catalytic amount of M(CO)5(THF) (M = Cr or W) in the presence of Et3N at room temperature gave ortho-substituted phenols 7 in good yields as valence isomerized products. In the absence of Et3N the reactions did not work at all. The reaction of a cyclopropane having an ester or an amide instead of an acetyl moiety with M(CO)5(THF) did not take place, whereas an ethynylvinylcyclopropane gave a mixture of 1- and 2-substituted 1,3,5-cycloheptatrienes. These valence isomerization reactions are assumed to proceed via the formation of vinylidene-metal intermediates 2 from terminal alkynyl moieties followed by [3,3]sigmatropy of 2 to give seven-membered carbene complexes 3. Copyright
REARRANGEMENT OF 2-HETARYLALKYLPYRIDINIUM SALTS
Rumyantsev, A. N.,Terenin, V. I.,Yudin, L. G.
, p. 300 - 303 (2007/10/02)
The rearrangement of 2-thienyl- and 2-furylalkylpyridinium salts to the corresponding anilines by the action of methylammonium sulfites has been studied.It has been shown that the rearrangement of these salts is accompanied in many cases by the formation of phenols and dealkylation products.The influence of the length of the alkyl chain between the heterocyclic rings on the ratio of the rearrangement products has been investigated.