CHIRAL LIGANDS CONTAINING HETEROATOMS. (S)-PROLINE AND (1R)-MENTHYLAMINE AS PRECURSORS OF MODIFIED LITHIUM ALUMINIUM HYDRIDE REAGENTS
A procedure for the preparation of (S)-2-pyrrolidine and of (S)-2-pyrrolidyl-N-oxalyl diamide from (S)-proline and (1R)-menthylamine is described.The results have shown the absence of racemization phenomena in the sequences adopted.The ligands obtained were used for chelating LiAlH4 in enantioselective reductions of phenyl ketones.